S100β Levels in CSF of Nonambulatory Dogs with Intervertebral Disk Disease Treated with Electroacupuncture
Joint Authors
Fonseca Pinto, Ana Carolina Brandão Campos
Murata Hayashi, Ayne
Matera, Julia Maria
Chadi, Gerson
Marvulle, Valdecir
Ruivo Maximino, Jessica
Cortopassi, Silvia Renata Gaido
Source
Journal of Veterinary Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The aim of the study was to investigate S100β levels in the cerebrospinal fluid of nonambulatory dogs with intervertebral disk disease treated with electroacupuncture: 10 dogs with thoracolumbar disk extrusion graded 3 to 5 (EA group) and 7 dogs without neurologic dysfunction (control group).
All dogs regained ambulation.
S100β was detected by Western blot analysis where EA group dogs were evaluated at two time points (M1 = before EA and M2 = when the dogs return ambulation) and at one time point from control group.
In EA group dogs M1-S100β levels were significantly higher than in control group.
EA group dogs were divided into subgroups A (n=7—early motor recovery; 6.7±7.8 days) and B (n=3—late motor recovery; 76±17.0 days).
M1-S100β levels were similar between subgroups A and B.
However, M2-S100β levels were significantly higher in subgroup B than in subgroup A.
An elevated S100β levels were observed in dogs with late motor recovery.
S100β may be associated with neuroplasticity following spinal cord injuries with intervertebral disk extrusion.
Further studies with larger numbers of subjects and control group with affected dogs are necessary to investigate the relationship between neurotrophic factors and electroacupuncture stimulation.
American Psychological Association (APA)
Murata Hayashi, Ayne& Fonseca Pinto, Ana Carolina Brandão Campos& Cortopassi, Silvia Renata Gaido& Marvulle, Valdecir& Ruivo Maximino, Jessica& Chadi, Gerson…[et al.]. 2013. S100β Levels in CSF of Nonambulatory Dogs with Intervertebral Disk Disease Treated with Electroacupuncture. Journal of Veterinary Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-480621
Modern Language Association (MLA)
Murata Hayashi, Ayne…[et al.]. S100β Levels in CSF of Nonambulatory Dogs with Intervertebral Disk Disease Treated with Electroacupuncture. Journal of Veterinary Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-480621
American Medical Association (AMA)
Murata Hayashi, Ayne& Fonseca Pinto, Ana Carolina Brandão Campos& Cortopassi, Silvia Renata Gaido& Marvulle, Valdecir& Ruivo Maximino, Jessica& Chadi, Gerson…[et al.]. S100β Levels in CSF of Nonambulatory Dogs with Intervertebral Disk Disease Treated with Electroacupuncture. Journal of Veterinary Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-480621
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480621