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Henoch-Schonlein Purpura—A Case Report and Review of the Literature
Joint Authors
Tong, Tommy R.
Hertan, Hilary I.
Sohagia, Amit B.
Gunturu, Srinivas Guptha
Source
Gastroenterology Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We describe a case of an adolescent male with Henoch-Schonlein purpura (HSP), presenting with cutaneous and gastrointestinal manifestations.
Endoscopy revealed diffuse ulcerations in the stomach, duodenum, and right colon.
Biopsies revealed a leukocytoclastic vasculitis in the skin and gastrointestinal tract.
Steroid therapy led to complete resolution of the symptoms.
HSP is the most common childhood vasculitis, and is characterized by the classic tetrad of nonthrombocytopenic palpable purpura, arthritis or arthralgias, gastrointestinal and renal involvement.
It is a systemic disease where antigen-antibody (IgA) complexes activate the alternate complement pathway, resulting in inflammation and small vessel vasculitis.
Mild disease resolves spontaneously, and symptomatic treatment alone is sufficient.
Systemic steroids are recommended for moderate to severe HSP.
The prognosis depends upon the extent of renal involvement, which requires close followup.
Early recognition of multiorgan involvement, especially outside of the typical age group, as in our adolescent patient, and appropriate intervention can mitigate the disease and limit organ damage.
American Psychological Association (APA)
Sohagia, Amit B.& Gunturu, Srinivas Guptha& Tong, Tommy R.& Hertan, Hilary I.. 2010. Henoch-Schonlein Purpura—A Case Report and Review of the Literature. Gastroenterology Research and Practice،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-483931
Modern Language Association (MLA)
Sohagia, Amit B.…[et al.]. Henoch-Schonlein Purpura—A Case Report and Review of the Literature. Gastroenterology Research and Practice No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-483931
American Medical Association (AMA)
Sohagia, Amit B.& Gunturu, Srinivas Guptha& Tong, Tommy R.& Hertan, Hilary I.. Henoch-Schonlein Purpura—A Case Report and Review of the Literature. Gastroenterology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-483931
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483931