Prevention of Peritendinous Adhesions Using an Electrospun DegraPol Polymer Tube : A Histological, Ultrasonographic, and Biomechanical Study in Rabbits
Joint Authors
Calcagni, Maurizio
Fessel, Gion
Müller, Angela
Giovanoli, Pietro
Meier Bürgisser, Gabriella
Buschmann, Johanna
Bonavoglia, Eliana
Snedeker, Jess G.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-02
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Purpose.
One of the great challenges in surgical tendon rupture repair is to minimize peritendinous adhesions.
In order to reduce adhesion formation, a physical barrier was applied to a sutured rabbit Achilles tendon, with two different immobilization protocols used postoperatively.
Methods.
Thirty New Zealand white rabbits received a laceration on the Achilles tendon, sutured with a 4-strand Becker suture, and half of the rabbits got a DegraPol tube at the repair site.
While fifteen rabbits had their treated hind leg in a 180° stretched position during 6 weeks (adhesion provoking immobilization), the other fifteen rabbits were recasted with a 150° position after 3 weeks (adhesion inhibiting immobilization).
Adhesion extent was analysed macroscopically, via ultrasound and histology.
Inflammation was determined histologically.
Biomechanical properties were analysed.
Results.
Application of a DegraPol tube reduced adhesion formation by approximately 20%—independently of the immobilization protocol.
Biomechanical properties of extracted specimen were not affected by the tube application.
There was no serious inflammatory reaction towards the implant material.
Conclusions.
Implantation of a DegraPol tube tightly set around a sutured tendon acts as a beneficial physical barrier and prevents adhesion formation significantly—without affecting the tendon healing process.
American Psychological Association (APA)
Meier Bürgisser, Gabriella& Calcagni, Maurizio& Müller, Angela& Bonavoglia, Eliana& Fessel, Gion& Snedeker, Jess G.…[et al.]. 2014. Prevention of Peritendinous Adhesions Using an Electrospun DegraPol Polymer Tube : A Histological, Ultrasonographic, and Biomechanical Study in Rabbits. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-488705
Modern Language Association (MLA)
Meier Bürgisser, Gabriella…[et al.]. Prevention of Peritendinous Adhesions Using an Electrospun DegraPol Polymer Tube : A Histological, Ultrasonographic, and Biomechanical Study in Rabbits. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-488705
American Medical Association (AMA)
Meier Bürgisser, Gabriella& Calcagni, Maurizio& Müller, Angela& Bonavoglia, Eliana& Fessel, Gion& Snedeker, Jess G.…[et al.]. Prevention of Peritendinous Adhesions Using an Electrospun DegraPol Polymer Tube : A Histological, Ultrasonographic, and Biomechanical Study in Rabbits. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-488705
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488705