An Overlapping Syndrome of Allergy and Immune Deficiency in Children
Author
Szczawinska-Poplonyk, Aleksandra
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Recurrent airway inflammations in children are an important clinical problem in pediatric practice.
An essential challenge is differentiation between allergic background and immune deficiency, which is a difficult task taking into consideration individual predisposition to atopy, immune system maturation in the early childhood, as well as exposition to environmental allergens and microbial antigens.
In this paper relationship between selected elements of innate and adaptive immunity, such as pattern-recognition receptors, complement components, dendritic cells, as well as immunoglobulins, and regulatory T lymph cells has been discussed.
Particular attention has been paid to these mechanisms of the immune response which, depending on settings and timing of activation, predispose to allergy or contribute to tolerogenic phenotype.
In the context of multifactorial conditioning of the innate and adaptive immunity governing the ultimate response and associations between allergy and immune deficiencies, these phenomena should be considered as pathogenetically not precluding, but as an overlapping syndrome.
American Psychological Association (APA)
Szczawinska-Poplonyk, Aleksandra. 2011. An Overlapping Syndrome of Allergy and Immune Deficiency in Children. Journal of Allergy،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-488884
Modern Language Association (MLA)
Szczawinska-Poplonyk, Aleksandra. An Overlapping Syndrome of Allergy and Immune Deficiency in Children. Journal of Allergy No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-488884
American Medical Association (AMA)
Szczawinska-Poplonyk, Aleksandra. An Overlapping Syndrome of Allergy and Immune Deficiency in Children. Journal of Allergy. 2011. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-488884
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488884