Analysis of IL-1α(−889) and IL-1B(+3953) Gene Polymorphism in Syrian Patients with Aggressive Periodontitis : A Pilot Study
Joint Authors
Khattab, Razan
Shhab, Reem
Shibani, Kenan
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Polymorphisms in IL-1 gene have been suggested to influence transcription of IL-1α and IL-1B and thereby the pathophysiology of periodontitis.
Using genotyping IL-1 test, a pilot study was conducted on 32 Syrian patients with aggressive periodontitis (AgP) and 35 healthy controls to investigate the association between the IL-1α(−889), IL-1B(+3953) gene polymorphisms and AgP among schoolchildren.
The results revealed a similar distribution of genotypes between patients and controls, and did not support an association between IL-1 gene polymorphisms and AgP, however, the association was significant in male patients only.
To determine and confirm any susceptible or resistant genes for AgP, future studies should use many target genes and well-defined related periodontal outcomes.
American Psychological Association (APA)
Shibani, Kenan& Shhab, Reem& Khattab, Razan. 2011. Analysis of IL-1α(−889) and IL-1B(+3953) Gene Polymorphism in Syrian Patients with Aggressive Periodontitis : A Pilot Study. ISRN Dentistry،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-490176
Modern Language Association (MLA)
Shibani, Kenan…[et al.]. Analysis of IL-1α(−889) and IL-1B(+3953) Gene Polymorphism in Syrian Patients with Aggressive Periodontitis : A Pilot Study. ISRN Dentistry No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-490176
American Medical Association (AMA)
Shibani, Kenan& Shhab, Reem& Khattab, Razan. Analysis of IL-1α(−889) and IL-1B(+3953) Gene Polymorphism in Syrian Patients with Aggressive Periodontitis : A Pilot Study. ISRN Dentistry. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-490176
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490176