25-Hydroxyvitamin D and Severity of Parkinson’s Disease
Joint Authors
Rahimi, Marzieh
Izadi Boroujeni, Maryam
Meamar, Rokhsareh
Tanhaei, Amir Pouya
Basiri, Keivan
Maracy, Mohammad
Chitsaz, Ahmad
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
A role for vitamin D deficiency in Parkinson’s disease (PD) has recently been proposed.
Given the growing body of evidence for the association of vitamin D with several neurodegenerative disorders and unavailability of any published study in the Middle East, the present study is aimed to determine the associations of circulating 25-hydroxyvitamin D (25OHD) levels with the severity of PD in an Iranian sample.
Methods.
In 109 patients, the severity of PD was evaluated by using Hoehn & Yahr (HR) stages and Unified Parkinson’s Disease Rating Stage (UPDRS) Part III compared with 25OHD level in a double-blind and cross-sectional study.
Results.
Mean ± SD levels of 25OHD were 28.5 ± 1.4 and 27.1 ± 1.5, for males and females, respectively.
Also, 38.4% of the patients showed deficiency levels of 25OHD (<20 ng/mL), and 72.8% had insufficient levels (<30 ng/mL).
High prevalence of 25OHD insufficiency in subjects with early disease was not associated with HR stage and UPDRS scores even after multivariate adjustment for possible confounders including disease duration.
Conclusions.
These findings are consistent with the possibility that vitamin D status does not seem to deteriorate during the early disease stages of PD.
Further studies are needed to reveal the natural role and significance of vitamin D insufficiency in PD.
American Psychological Association (APA)
Chitsaz, Ahmad& Maracy, Mohammad& Basiri, Keivan& Izadi Boroujeni, Maryam& Tanhaei, Amir Pouya& Rahimi, Marzieh…[et al.]. 2013. 25-Hydroxyvitamin D and Severity of Parkinson’s Disease. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-490700
Modern Language Association (MLA)
Chitsaz, Ahmad…[et al.]. 25-Hydroxyvitamin D and Severity of Parkinson’s Disease. International Journal of Endocrinology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-490700
American Medical Association (AMA)
Chitsaz, Ahmad& Maracy, Mohammad& Basiri, Keivan& Izadi Boroujeni, Maryam& Tanhaei, Amir Pouya& Rahimi, Marzieh…[et al.]. 25-Hydroxyvitamin D and Severity of Parkinson’s Disease. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-490700
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490700