Serum Interleukin 17 Levels in Patients with Crohn’s Disease : Real Life Data
Joint Authors
Aydin, Kubra
Sokmen, Hacı Mehmet
Kahraman, Resul
Korachi, May
Cengiz, Mustafa
Ozdil, Kamil
Sahin, Abdurrahman
Calhan, Turan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The aim of this study was to investigate serum IL17 levels in patients with Crohn’s disease (CD) and to investigate the relationship between serum IL17 levels with disease activity.
Methods.
Fifty patients with CD and sex- and age-matched 40 healthy controls were included in the study.
The serum IL17 levels, complete blood count, blood chemistry, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels were measured, and Crohn’s disease activity was calculated using Crohn’s disease activity index (CDAI).
Results.
The mean serum IL17 level of CD patients did not differ from those of healthy controls (P>0.05).
There was no difference between the mean serum IL levels of active CD patients and of quiescent CD patients (P>0.05).
However, the mean IL17 level of active patients was lower than of control subjects (P=0.02).
Serum IL17 was not correlated with inflammatory markers (ESR, CRP, white blood count, platelet count, and albumin) and CDAI.
Conclusions.
Peripheral blood serum IL17 levels of CD patients were not higher than of healthy controls, and also, serum IL17 level was not correlated with clinical disease activity.
Peripheral IL17 measurement is not a useful tool for detecting and monitoring Crohn’s disease which is understood to have complex etiopathogenesis.
American Psychological Association (APA)
Sahin, Abdurrahman& Calhan, Turan& Cengiz, Mustafa& Kahraman, Resul& Aydin, Kubra& Ozdil, Kamil…[et al.]. 2014. Serum Interleukin 17 Levels in Patients with Crohn’s Disease : Real Life Data. Disease Markers،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-490861
Modern Language Association (MLA)
Sahin, Abdurrahman…[et al.]. Serum Interleukin 17 Levels in Patients with Crohn’s Disease : Real Life Data. Disease Markers No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-490861
American Medical Association (AMA)
Sahin, Abdurrahman& Calhan, Turan& Cengiz, Mustafa& Kahraman, Resul& Aydin, Kubra& Ozdil, Kamil…[et al.]. Serum Interleukin 17 Levels in Patients with Crohn’s Disease : Real Life Data. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-490861
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490861