Optimisation of Simultaneous Tl-201Tc-99m Dual Isotope Reconstruction with Monte-Carlo-Based Scatter Correction
Joint Authors
Kuikka, Jyrki T.
Sohlberg, Antti
Kangasmaa, Tuija
Source
International Journal of Molecular Imaging
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Simultaneous Tl-201/Tc-99m dual isotope myocardial perfusion SPECT is seriously hampered by down-scatter from Tc-99m into the Tl-201 energy window.
This paper presents and optimises the ordered-subsets-expectation-maximisation-(OS-EM-) based reconstruction algorithm, which corrects the down-scatter using an efficient Monte Carlo (MC) simulator.
The algorithm starts by first reconstructing the Tc-99m image with attenuation, collimator response, and MC-based scatter correction.
The reconstructed Tc-99m image is then used as an input for an efficient MC-based down-scatter simulation of Tc-99m photons into the Tl-201 window.
This down-scatter estimate is finally used in the Tl-201 reconstruction to correct the crosstalk between the two isotopes.
The mathematical 4D NCAT phantom and physical cardiac phantoms were used to optimise the number of OS-EM iterations where the scatter estimate is updated and the number of MC simulated photons.
The results showed that two scatter update iterations and 105 simulated photons are enough for the Tc-99m and Tl-201 reconstructions, whereas 106 simulated photons are needed to generate good quality down-scatter estimates.
With these parameters, the entire Tl-201/Tc-99m dual isotope reconstruction can be accomplished in less than 3 minutes.
American Psychological Association (APA)
Kangasmaa, Tuija& Kuikka, Jyrki T.& Sohlberg, Antti. 2012. Optimisation of Simultaneous Tl-201Tc-99m Dual Isotope Reconstruction with Monte-Carlo-Based Scatter Correction. International Journal of Molecular Imaging،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-491283
Modern Language Association (MLA)
Kangasmaa, Tuija…[et al.]. Optimisation of Simultaneous Tl-201Tc-99m Dual Isotope Reconstruction with Monte-Carlo-Based Scatter Correction. International Journal of Molecular Imaging No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-491283
American Medical Association (AMA)
Kangasmaa, Tuija& Kuikka, Jyrki T.& Sohlberg, Antti. Optimisation of Simultaneous Tl-201Tc-99m Dual Isotope Reconstruction with Monte-Carlo-Based Scatter Correction. International Journal of Molecular Imaging. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-491283
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491283