Guillain-Barré Syndrome following Treatment with Sunitinib Malate
Joint Authors
Titianu, Mirela
Kulairi, Zain
Kumar, Sanjeev
Saha, Sandip
Kanaan, Ziad
Source
Case Reports in Oncological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-2, 2 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-11
Country of Publication
Egypt
No. of Pages
2
Main Subjects
Abstract EN
Sunitinib malate (Sutent, SU011248) is an oral multitargeted tyrosine kinase inhibitor (TKI) used for the treatment of metastatic renal cell carcinoma and imatinib (Gleevec)—resistant gastrointestinal stromal tumor (GIST) with few reported side effects including asthenia, myelosuppression, diarrhea, and mucositis.
Scarce literature exists regarding the rare but often serious toxicities of sunitinib.
Autoimmune and neurological side effects have been linked to sunitinib’s inhibition of VEGF receptors with a corresponding increase in VEGF levels, which is associated with development of different neuropathies.
We hereby report an interesting case of Guillain-Barré syndrome in a middle-aged patient with metastatic renal cell carcinoma following sunitinib treatment.
American Psychological Association (APA)
Kanaan, Ziad& Kulairi, Zain& Titianu, Mirela& Saha, Sandip& Kumar, Sanjeev. 2014. Guillain-Barré Syndrome following Treatment with Sunitinib Malate. Case Reports in Oncological Medicine،Vol. 2014, no. 2014, pp.1-2.
https://search.emarefa.net/detail/BIM-492496
Modern Language Association (MLA)
Kanaan, Ziad…[et al.]. Guillain-Barré Syndrome following Treatment with Sunitinib Malate. Case Reports in Oncological Medicine No. 2014 (2014), pp.1-2.
https://search.emarefa.net/detail/BIM-492496
American Medical Association (AMA)
Kanaan, Ziad& Kulairi, Zain& Titianu, Mirela& Saha, Sandip& Kumar, Sanjeev. Guillain-Barré Syndrome following Treatment with Sunitinib Malate. Case Reports in Oncological Medicine. 2014. Vol. 2014, no. 2014, pp.1-2.
https://search.emarefa.net/detail/BIM-492496
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492496