Noninvasive Approach to Focal Cortical Dysplasias : Clinical, EEG, and Neuroimaging Features

Joint Authors

Papayannis, Cristina
Muravchik, Carlos H.
Seifer, Gustavo
Kochen, Silvia
Blenkmann, Alejandro
Consalvo, Damián
Princich, Juan Pablo

Source

Epilepsy Research and Treatment

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-03-05

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Diseases

Abstract EN

Purpose.

The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients with MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates of epilepsy surgery.

Methods.

Twenty patients were evaluated prospectively between 2007 and 2010 with comprehensive clinical evaluation, video-electroencephalography, diffusion tensor imaging (DTI), and high-resolution EEG to localize the equivalent current dipole (ECD).

Key Findings.

In 11 cases with white matter asymmetries in DTI the ECDs were located next to lesion on MRI with mean distance of 14.63 millimeters with topographical correlation with the EZ.

Significance.

We could establish a hypothesis of EZ based on Video-EEG, high-resolution EEG, ECD method, MRI, and DTI.

These results are consistent with the hypothesis that the EZ in the FCD is complex and is often larger than visible lesion in MRI.

American Psychological Association (APA)

Seifer, Gustavo& Blenkmann, Alejandro& Princich, Juan Pablo& Consalvo, Damián& Papayannis, Cristina& Muravchik, Carlos H.…[et al.]. 2012. Noninvasive Approach to Focal Cortical Dysplasias : Clinical, EEG, and Neuroimaging Features. Epilepsy Research and Treatment،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-494630

Modern Language Association (MLA)

Seifer, Gustavo…[et al.]. Noninvasive Approach to Focal Cortical Dysplasias : Clinical, EEG, and Neuroimaging Features. Epilepsy Research and Treatment No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-494630

American Medical Association (AMA)

Seifer, Gustavo& Blenkmann, Alejandro& Princich, Juan Pablo& Consalvo, Damián& Papayannis, Cristina& Muravchik, Carlos H.…[et al.]. Noninvasive Approach to Focal Cortical Dysplasias : Clinical, EEG, and Neuroimaging Features. Epilepsy Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-494630

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-494630