Characterization of pPCP1 Plasmids in Yersinia pestis Strains Isolated from the Former Soviet Union

Joint Authors

Rashid, Mohammed H.
Sulakvelidze, Alexander
Bakanidze, Lela
Sozhamannan, Shanmuga
Bishop-Lilly, Kimberly A.
Imnadze, Paata
Revazishvili, Tamara
Rajanna, Chythanya
Morris, J. Glenn
Tsanava, Shota
Gibbons, Henry S.
Chubinidze, Svetlana

Source

International Journal of Microbiology

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-12-20

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Natural & Life Sciences (Multidisciplinary)
Medicine

Abstract EN

Complete sequences of 9.5-kb pPCP1 plasmids in three Yersinia pestis strains from the former Soviet Union (FSU) were determined and compared with those of pPCP1 plasmids in three well-characterized, non-FSU Y.

pestis strains (KIM, CO92, and 91001).

Two of the FSU plasmids were from strains C2614 and C2944, isolated from plague foci in Russia, and one plasmid was from strain C790 from Kyrgyzstan.

Sequence analyses identified four sequence types among the six plasmids.

The pPCP1 plasmids in the FSU strains were most genetically related to the pPCP1 plasmid in the KIM strain and least related to the pPCP1 plasmid in Y.

pestis 91001.

The FSU strains generally had larger pPCP1 plasmid copy numbers compared to strain CO92.

Expression of the plasmid's pla gene was significantly (P≤.05) higher in strain C2944 than in strain CO92.

Given pla's role in Y.

pestis virulence, this difference may have important implications for the strain's virulence.

American Psychological Association (APA)

Rajanna, Chythanya& Revazishvili, Tamara& Rashid, Mohammed H.& Chubinidze, Svetlana& Bakanidze, Lela& Tsanava, Shota…[et al.]. 2010. Characterization of pPCP1 Plasmids in Yersinia pestis Strains Isolated from the Former Soviet Union. International Journal of Microbiology،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-496636

Modern Language Association (MLA)

Rajanna, Chythanya…[et al.]. Characterization of pPCP1 Plasmids in Yersinia pestis Strains Isolated from the Former Soviet Union. International Journal of Microbiology No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-496636

American Medical Association (AMA)

Rajanna, Chythanya& Revazishvili, Tamara& Rashid, Mohammed H.& Chubinidze, Svetlana& Bakanidze, Lela& Tsanava, Shota…[et al.]. Characterization of pPCP1 Plasmids in Yersinia pestis Strains Isolated from the Former Soviet Union. International Journal of Microbiology. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-496636

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-496636