Effect of Formula Feeding and Breastfeeding on Child Growth, Infant Mortality, and HIV Transmission in Children Born to HIV-Infected Pregnant Women Who Received Triple Antiretroviral Therapy in a Resource-Limited Setting : Data from an HIV Cohort Study in India
Joint Authors
Naik, Praveen Kumar
Bachu, Lakshminarayana
Alvarez-Uria, Gerardo
Midde, Manoranjan
Pakam, Raghavakalyan
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
We describe a programme for the prevention of mother-to-child transmission (PMTCT) of HIV that provided universal antiretroviral therapy (ART) to all pregnant women regardless of the CD4 lymphocyte count and formula feeding for children with high risk of HIV transmission through breastfeeding in a district of India.
The overall rate of HIV transmission was 3.7%.
Although breastfeeding added a 3.1% additional risk of HIV acquisition, formula-fed infants had significantly higher risk of death compared to breastfed infants.
The cumulative 12-month mortality was 9.6% for formula-fed infants versus 0.68% for breastfed infants.
Anthropometric markers (weight, length/height, weight for length/height, body mass index, head circumference, mid-upper arm circumference, triceps skinfold, and subscapular skinfold) showed that formula-fed infants experience severe malnutrition during the first two months of life.
We did not observe any death after rapid weaning at 5-6 months in breastfed infants.
The higher-free-of HIV survival in breastfed infants and the low rate of HIV transmission found in this study support the implementation of PMTCT programmes with universal ART to all HIV-infected pregnant women and breastfeeding in order to reduce HIV transmission without increasing infant mortality in developing countries.
American Psychological Association (APA)
Alvarez-Uria, Gerardo& Midde, Manoranjan& Pakam, Raghavakalyan& Bachu, Lakshminarayana& Naik, Praveen Kumar. 2012. Effect of Formula Feeding and Breastfeeding on Child Growth, Infant Mortality, and HIV Transmission in Children Born to HIV-Infected Pregnant Women Who Received Triple Antiretroviral Therapy in a Resource-Limited Setting : Data from an HIV Cohort Study in India. ISRN Pediatrics،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-496902
Modern Language Association (MLA)
Alvarez-Uria, Gerardo…[et al.]. Effect of Formula Feeding and Breastfeeding on Child Growth, Infant Mortality, and HIV Transmission in Children Born to HIV-Infected Pregnant Women Who Received Triple Antiretroviral Therapy in a Resource-Limited Setting : Data from an HIV Cohort Study in India. ISRN Pediatrics No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-496902
American Medical Association (AMA)
Alvarez-Uria, Gerardo& Midde, Manoranjan& Pakam, Raghavakalyan& Bachu, Lakshminarayana& Naik, Praveen Kumar. Effect of Formula Feeding and Breastfeeding on Child Growth, Infant Mortality, and HIV Transmission in Children Born to HIV-Infected Pregnant Women Who Received Triple Antiretroviral Therapy in a Resource-Limited Setting : Data from an HIV Cohort Study in India. ISRN Pediatrics. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-496902
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496902