Subjects with Discordant Airways Obstruction : Lost between Spirometric Definitions of COPD
Joint Authors
Studnicka, Michael
Buist, Sonia A.
Kaiser, Bernhard
Schirnhofer, Lea
Mannino, David M.
Lamprecht, Bernd
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Since the FEV1/FVC ratio declines with age, using the fixed ratio of 0.70 leads to overdiagnosis of COPD in older populations and underdiagnosis among young adults.
Objective.
To evaluate whether discordant obstructive cases (FEV1/FVC < 0.70 but ≥LLN) are a healthy population or have clinical features that would place them at increased risk.
Methods.
We used post-bronchodilator spirometry data from the population-based Austrian Burden of Obstructive Lung Disease (BOLD) study.
Those with post-bronchodilator FEV1/FVC ratio Participants with post-bronchodilator FEV1/FVC ratio ≥LLN but <0.70 were defined as discordant obstructive cases. Results. Discordant obstructive cases were more likely to be older, male and never-smokers. Additionally they had less respiratory symptoms and less severe impairment of FEV1. However, discordant obstructive cases reported significantly more often a diagnosis of heart disease than subjects with normal lung function (27.2% vs 7.3%, P=.015). Conclusion. The clinical profile of discordant obstructive cases includes potentially important comorbid disease.
American Psychological Association (APA)
Lamprecht, Bernd& Schirnhofer, Lea& Kaiser, Bernhard& Buist, Sonia A.& Mannino, David M.& Studnicka, Michael. 2011. Subjects with Discordant Airways Obstruction : Lost between Spirometric Definitions of COPD. Pulmonary Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-497397
Modern Language Association (MLA)
Lamprecht, Bernd…[et al.]. Subjects with Discordant Airways Obstruction : Lost between Spirometric Definitions of COPD. Pulmonary Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-497397
American Medical Association (AMA)
Lamprecht, Bernd& Schirnhofer, Lea& Kaiser, Bernhard& Buist, Sonia A.& Mannino, David M.& Studnicka, Michael. Subjects with Discordant Airways Obstruction : Lost between Spirometric Definitions of COPD. Pulmonary Medicine. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-497397
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497397