An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles

Joint Authors

Amani, Amir
Faramarzi, Mohammad Ali
Amini, Mohsen
Mottaghi-Dastjerdi, Negar
Esmaeilzadeh, Elina
Naghibzadeh, Majid

Source

Journal of Nanomaterials

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-07-14

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Engineering Sciences and Information Technology
Chemistry
Civil Engineering

Abstract EN

The aim of this study was to investigate the interactions between α-tocopherol and chitosan molecules prepared subsequent to preparation of α-tocopherol-loaded chitosan nanoparticles using ultrasonication.

Dynamic light scattering (DLS) and scanning electron microscopy (SEM) analyses showed semispherical particles with an average size of approximately 350 nm.

Also from reconstitution test, α-tocopherol was suggested as stabilizing agent during lyophilization/reconstitution process.

The zeta potentials of chitosan and α-tocopherol nanoparticles were larger than ±30 mV, representing suitable stability.

Data obtained from FTIR showed possibility of chemical interaction between chitosan and α-tocopherol.

Furthermore, the results from FTIR, NMR, and XRD spectroscopy confirmed electrostatic interactions between the two molecules.

Overall, this procedure could be considered as a facile method to prepare α-tocopherol-loaded nanoparticles.

American Psychological Association (APA)

Naghibzadeh, Majid& Amani, Amir& Amini, Mohsen& Esmaeilzadeh, Elina& Mottaghi-Dastjerdi, Negar& Faramarzi, Mohammad Ali. 2010. An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles. Journal of Nanomaterials،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-500604

Modern Language Association (MLA)

Naghibzadeh, Majid…[et al.]. An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles. Journal of Nanomaterials No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-500604

American Medical Association (AMA)

Naghibzadeh, Majid& Amani, Amir& Amini, Mohsen& Esmaeilzadeh, Elina& Mottaghi-Dastjerdi, Negar& Faramarzi, Mohammad Ali. An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles. Journal of Nanomaterials. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-500604

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-500604