An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles
Joint Authors
Amani, Amir
Faramarzi, Mohammad Ali
Amini, Mohsen
Mottaghi-Dastjerdi, Negar
Esmaeilzadeh, Elina
Naghibzadeh, Majid
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-07-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
The aim of this study was to investigate the interactions between α-tocopherol and chitosan molecules prepared subsequent to preparation of α-tocopherol-loaded chitosan nanoparticles using ultrasonication.
Dynamic light scattering (DLS) and scanning electron microscopy (SEM) analyses showed semispherical particles with an average size of approximately 350 nm.
Also from reconstitution test, α-tocopherol was suggested as stabilizing agent during lyophilization/reconstitution process.
The zeta potentials of chitosan and α-tocopherol nanoparticles were larger than ±30 mV, representing suitable stability.
Data obtained from FTIR showed possibility of chemical interaction between chitosan and α-tocopherol.
Furthermore, the results from FTIR, NMR, and XRD spectroscopy confirmed electrostatic interactions between the two molecules.
Overall, this procedure could be considered as a facile method to prepare α-tocopherol-loaded nanoparticles.
American Psychological Association (APA)
Naghibzadeh, Majid& Amani, Amir& Amini, Mohsen& Esmaeilzadeh, Elina& Mottaghi-Dastjerdi, Negar& Faramarzi, Mohammad Ali. 2010. An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles. Journal of Nanomaterials،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-500604
Modern Language Association (MLA)
Naghibzadeh, Majid…[et al.]. An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles. Journal of Nanomaterials No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-500604
American Medical Association (AMA)
Naghibzadeh, Majid& Amani, Amir& Amini, Mohsen& Esmaeilzadeh, Elina& Mottaghi-Dastjerdi, Negar& Faramarzi, Mohammad Ali. An Insight into the Interactions between α-Tocopherol and Chitosan in Ultrasound-Prepared Nanoparticles. Journal of Nanomaterials. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-500604
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500604