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Acupuncture at “Zusanli” (St.36) and “Sanyinjiao” (SP.6) Points on the Gastrointestinal Tract : A Study of the Bioavailability of 99mTc-Sodium Pertechnetate in Rats
Joint Authors
Manoel, Cristiano V.
França, Daisy L. M.
Senna-Fernandes, Vasco
Bernardo-Filho, Mario
Santos-Filho, Sebastião D.
de Souza, Deise
Guimarães, Marco Antonio M.
Cortez, Célia M.
Sousa, Rafael S.
Santos, Kelly C. M.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The objective of this study is to investigate the differences of acupuncture effect between the Zusanli (St.36) and Sanyinjiao (SP.6) points on the gastrointestinal-tract (GIT) segment performed by the bioavailability of 99mTc-sodium-pertechnetate (Na99mTcO4) in rats.
Male Wistar rats (n = 21) were allocated into three groups of seven each.
Group 1 was treated by acupuncture bilaterally at St.36; Group 2 at SP.6; and Group 3 was untreated (control).
After 10 min of needle insertion in anesthetized rats, 0.3 mL of Na99mTcO4 (7.4 MBq) was injected via ocular-plexus.
After 20 min, the exitus of animals was induced by cervical-dislocation and GIT organs isolated.
However, immediately before the exitus procedure, blood was collected by cardiac-puncture for blood radio-labeling (BRL).
The radioactivity uptake of the blood constituents was calculated together with the GIT organs by a well gamma counter.
The percentage of injected dose per gram of tissue (%ID/g) of Na99mTcO4 was calculated for each GIT organs, while BRL was calculated in %ID.
According to the one-way ANOVA, the stomach, jejunum, ileum from the treated groups (Group 1 and Group 2) had significant differences compared to the controls (Group 3).
However, between the treated groups (Group 1 and Group 2), there were significant differences (P < .05) in the stomach, jejunum, ileum, cecum, transverse and rectum.
In BRL analysis, Group 2 showed significant increase and decrease of the insoluble and soluble fractions of the blood cells, respectively (P < .0001).
The authors suggest that St.36 may have a tendency of up-regulation effect on GIT, whereas SP.6, down-regulation effect.
However, further rigorous experimental studies to examine the effectiveness of acupuncture in either acupuncture points need to be carried out.
American Psychological Association (APA)
Senna-Fernandes, Vasco& França, Daisy L. M.& de Souza, Deise& Santos, Kelly C. M.& Sousa, Rafael S.& Manoel, Cristiano V.…[et al.]. 2010. Acupuncture at “Zusanli” (St.36) and “Sanyinjiao” (SP.6) Points on the Gastrointestinal Tract : A Study of the Bioavailability of 99mTc-Sodium Pertechnetate in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-501010
Modern Language Association (MLA)
Senna-Fernandes, Vasco…[et al.]. Acupuncture at “Zusanli” (St.36) and “Sanyinjiao” (SP.6) Points on the Gastrointestinal Tract : A Study of the Bioavailability of 99mTc-Sodium Pertechnetate in Rats. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-501010
American Medical Association (AMA)
Senna-Fernandes, Vasco& França, Daisy L. M.& de Souza, Deise& Santos, Kelly C. M.& Sousa, Rafael S.& Manoel, Cristiano V.…[et al.]. Acupuncture at “Zusanli” (St.36) and “Sanyinjiao” (SP.6) Points on the Gastrointestinal Tract : A Study of the Bioavailability of 99mTc-Sodium Pertechnetate in Rats. Evidence-Based Complementary and Alternative Medicine. 2010. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-501010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501010