What Is the Most Appropriate Source for Hematopoietic Stem Cell Transplantation? Peripheral Stem CellBone MarrowCord Blood
Joint Authors
Tekgunduz, Emre
Altuntas, Fevzi
Sirinoglu Demiriz, Itır
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The introduction of peripheral stem cell (PSC) and cord blood (CB) as an alternative to bone marrow (BM) recently has caused important changes on hematopoietic stem cell transplantation (HSCT) practice.
According to the CIBMTR data, there has been a significant decrease in the use of bone marrow and increase in the use of PSC and CB as the stem cell source for HSCT performed during 1997–2006 period for patients under the age of 20.
On the other hand, the stem cell source in 70% of the HSCT procedures performed for patients over the age of 20 was PSC and the second most preferred stem cell source was bone marrow.
CB usage is very limited for the adult population.
Primary disease, stage, age, time and urgency of transplantation, HLA match between the patient and the donor, stem cell quantity, and the experience of the transplantation center are some of the associated factors for the selection of the appropriate stem cell source.
Unfortunately, there is no prospective randomized study aimed to facilitate the selection of the correct source between CB, PSC, and BM.
In this paper, we would like to emphasize the data on stem cell selection in light of the current knowledge for patient populations according to their age and primary disease.
American Psychological Association (APA)
Sirinoglu Demiriz, Itır& Tekgunduz, Emre& Altuntas, Fevzi. 2012. What Is the Most Appropriate Source for Hematopoietic Stem Cell Transplantation? Peripheral Stem CellBone MarrowCord Blood. Bone Marrow Research،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-501801
Modern Language Association (MLA)
Sirinoglu Demiriz, Itır…[et al.]. What Is the Most Appropriate Source for Hematopoietic Stem Cell Transplantation? Peripheral Stem CellBone MarrowCord Blood. Bone Marrow Research No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-501801
American Medical Association (AMA)
Sirinoglu Demiriz, Itır& Tekgunduz, Emre& Altuntas, Fevzi. What Is the Most Appropriate Source for Hematopoietic Stem Cell Transplantation? Peripheral Stem CellBone MarrowCord Blood. Bone Marrow Research. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-501801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501801