The NT-ProBNP Test in Subjects with End-Stage Renal Disease on Hemodialysis Presenting with Acute Dyspnea : Is Knowing Worth the Cost?
Joint Authors
Avila, Jose
Milcarek, Barry
Kasama, Richard
Mok, Shaffer R. S.
Source
Emergency Medicine International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
The NT-ProBNP/BNP test has been validated as a marker for determining the etiology of acute dyspnea.
In the setting of end-stage renal disease on hemodialysis (ESRD on HD), the utility of the NT-ProBNP/BNP test has not been validated.
This study examines the clinical utility of the NT-ProBNP test in the setting of ESRD on HD patients presenting with acute dyspnea.
Methods.
A retrospective case series of 250 subjects were admitted to Cooper University Hospital, 07/2010-03/2011, with ESRD and HD presenting with dyspnea.
The incidences of echocardiography, cardiology consultation, and NT-ProBNP elevated and normal were examined.
Correlation coefficients were calculated for NT-ProBNP with age (years), estimated dry weight (kg), amount of fluid removed (L), and ejection fraction (EF in %) among other echocardiography parameters.
Results.
Of the total sample 235 patients had NT-ProBNP levels performed.
Cardiology consults were placed in 68.8% and 58% who underwent echocardiography.
Of those for whom an echocardiography was performed estimated mean EFs of 54.6%, 50.8%, and 61.7% were observed among the NT-ProBNP elevated group, normal group, and no NT-ProBNP group, respectively.
No differences were detected in all other echocardiography measurements.
No correlation was observed between NT-ProBNP and age (r=0.05), baseline EDW (r=−0.09), amount of fluid removed (r=0.07), or EF (r=0.02).
Conclusion.
In the setting of ESRD on HD, the NT-ProBNP test has no clinical utility in determining the etiology of acute dyspnea.
This can be demonstrated through echocardiographic and therapeutic parameters measured in this study.
American Psychological Association (APA)
Mok, Shaffer R. S.& Avila, Jose& Milcarek, Barry& Kasama, Richard. 2013. The NT-ProBNP Test in Subjects with End-Stage Renal Disease on Hemodialysis Presenting with Acute Dyspnea : Is Knowing Worth the Cost?. Emergency Medicine International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-502026
Modern Language Association (MLA)
Mok, Shaffer R. S.…[et al.]. The NT-ProBNP Test in Subjects with End-Stage Renal Disease on Hemodialysis Presenting with Acute Dyspnea : Is Knowing Worth the Cost?. Emergency Medicine International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-502026
American Medical Association (AMA)
Mok, Shaffer R. S.& Avila, Jose& Milcarek, Barry& Kasama, Richard. The NT-ProBNP Test in Subjects with End-Stage Renal Disease on Hemodialysis Presenting with Acute Dyspnea : Is Knowing Worth the Cost?. Emergency Medicine International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-502026
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502026