Inclusion Complexes of Sunscreen Agents with β-Cyclodextrin : Spectroscopic and Molecular Modeling Studies
Joint Authors
al-Rawashdeh, Nathir A. F.
al-Sadeh, Khaled S.
al-Bitar, Mohammad Bassam
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-02
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The inclusion complexes of selected sunscreen agents, namely, oxybenzone (Oxy), octocrylene (Oct), and ethylhexyl-methoxycinnamate (Cin) with β-cyclodextrin (β-CD) were studied by UV-Vis spectroscopy, differential scanning calorimetry (DSC), 13C NMR techniques, and molecular mechanics (MM) calculations and modeling.
Molecular modeling (MM) study of the entire process of the formation of 1 : 1 stoichiometry sunscreen agent/β-cyclodextrin structures has been used to contribute to the understanding and rationalization of the experimental results.
Molecular mechanics calculations, together with 13C NMR measurements, for the complex with β-CD have been used to describe details of the structural, energetic, and dynamic features of host-guest complex.
Accurate structures of CD inclusion complexes have been derived from molecular mechanics (MM) calculations and modeling.
The photodegradation reaction of the sunscreen agents' molecules in lotion was explored using UV-Vis spectroscopy.
It has been demonstrated that the photostability of these selected sunscreen agents has been enhanced upon forming inclusion complexes with β-CD in lotion.
The results of this study demonstrate that β-CD can be utilized as photostabilizer additive for enhancing the photostability of the selected sunscreen agents' molecules.
American Psychological Association (APA)
al-Rawashdeh, Nathir A. F.& al-Sadeh, Khaled S.& al-Bitar, Mohammad Bassam. 2013. Inclusion Complexes of Sunscreen Agents with β-Cyclodextrin : Spectroscopic and Molecular Modeling Studies. Journal of Spectroscopy،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-502488
Modern Language Association (MLA)
al-Rawashdeh, Nathir A. F.…[et al.]. Inclusion Complexes of Sunscreen Agents with β-Cyclodextrin : Spectroscopic and Molecular Modeling Studies. Journal of Spectroscopy No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-502488
American Medical Association (AMA)
al-Rawashdeh, Nathir A. F.& al-Sadeh, Khaled S.& al-Bitar, Mohammad Bassam. Inclusion Complexes of Sunscreen Agents with β-Cyclodextrin : Spectroscopic and Molecular Modeling Studies. Journal of Spectroscopy. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-502488
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502488