Regenerative Therapies Using Cell Sheet-Based Tissue Engineering for Cardiac Disease
Joint Authors
Shimizu, Tatsuya
Yamato, Masayuki
Haraguchi, Yuji
Okano, Teruo
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
At present, cardiac diseases are a major cause of morbidity and mortality in the world.
Recently, a cell-based regenerative medicine has appeared as one of the most potential and promising therapies for improving cardiac diseases.
As a new generational cell-based regenerative therapy, tissue engineering is focused.
Our laboratory has originally developed cell sheet-based scaffold-free tissue engineering.
Three-dimensional myocardial tissue fabricated by stacking cardiomyocyte sheets, which are tightly interconnected to each other through gap junctions, beats simultaneously and macroscopically and shows the characteristic structures of native heart tissue.
Cell sheet-based therapy cures the damaged heart function of animal models and is clinically applied.
Cell sheet-based tissue engineering has a promising and enormous potential in myocardial tissue regenerative medicine and will cure many patients suffering from severe cardiac disease.
This paper summarizes cell sheet-based tissue engineering and its satisfactory therapeutic effects on cardiac disease.
American Psychological Association (APA)
Haraguchi, Yuji& Shimizu, Tatsuya& Yamato, Masayuki& Okano, Teruo. 2011. Regenerative Therapies Using Cell Sheet-Based Tissue Engineering for Cardiac Disease. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-502776
Modern Language Association (MLA)
Haraguchi, Yuji…[et al.]. Regenerative Therapies Using Cell Sheet-Based Tissue Engineering for Cardiac Disease. Cardiology Research and Practice No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-502776
American Medical Association (AMA)
Haraguchi, Yuji& Shimizu, Tatsuya& Yamato, Masayuki& Okano, Teruo. Regenerative Therapies Using Cell Sheet-Based Tissue Engineering for Cardiac Disease. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-502776
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502776