Diagnosis and Management of Pulmonary Arterial Hypertension
Joint Authors
Klinger, James R.
Martin, Douglas
Houtchens, Jeanne
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-20
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Pulmonary arterial hypertension is a rare disease, which requires a high index of suspicion to diagnose when patients initially present.
Initial symptoms can be nonspecific and include complaints such as fatigue and mild dyspnea.
Once the disease is suspected, echocardiography is used to estimate the pulmonary arterial (PA) pressure and to exclude secondary causes of elevated PA pressures such as left heart disease.
Right heart catheterization with vasodilator challenge is critical to the proper assessment of pulmonary hemodynamics and to determine whether patients are likely to benefit from vasodilator therapy.
Pathologically, the disease is characterized by deleterious remodeling of the distal pulmonary arterial and arteriolar circulation, which results in increased pulmonary vascular resistance.
In the last fifteen years, medications from three different classes have been approved for the treatment of pulmonary arterial hypertension.
These include the prostanoids, endothelin receptor antagonists, and phosphodiesterase-5 inhibitors.
American Psychological Association (APA)
Houtchens, Jeanne& Martin, Douglas& Klinger, James R.. 2011. Diagnosis and Management of Pulmonary Arterial Hypertension. Pulmonary Medicine،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-502837
Modern Language Association (MLA)
Houtchens, Jeanne…[et al.]. Diagnosis and Management of Pulmonary Arterial Hypertension. Pulmonary Medicine No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-502837
American Medical Association (AMA)
Houtchens, Jeanne& Martin, Douglas& Klinger, James R.. Diagnosis and Management of Pulmonary Arterial Hypertension. Pulmonary Medicine. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-502837
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502837