Results of Second-Look Laparotomy in Advanced Ovarian Cancer : One Single Center Experience
Joint Authors
Hechiche, Monia
Rahal, Khaled
Chargui, Riadh
Ben Hassouna, Jamel
Damak, Tarak
Source
ISRN Obstetrics and Gynecology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
The goal of the study was to analyse the results of 85 cases of second-look laparotomy (SLL) and explore the influence of this procedure on survival.
Patients and Methods.
We reviewed retrospectively 85 cases of SLL collected and treated in our institute between 1994 and 2003.
Results.
Complete pathologic response (CPR) was 25.8%, microscopic disease (Rmicro) was 38.8%, and macroscopic disease (Rmacro) was 35.4%.
In patients with negative SLL results, disease recurrence was diagnosed in 41%.
The 3- and 5-year overall survival rates for the entire population were 91% and 87%, respectively.
The 3- and 5-year disease-free survivals were, respectively, 76.3% and 58.5% in negative SLL versus 55.7% and 16% in positive SLL.
The difference between the group of patients with complete response (76%) and the patients with residual microscopic disease (72%) was not significant.
The tumoral residuum after initial surgery was the only prognostic factor influencing significantly the disease-free survival.
On Cox regression model analysis, only initial tumoral residuum (P=0.04) and tumoral residuum after SLL (P=0.02) were independent prognostic factors for survival.
Conclusions.
The most important advantage of SLL is the early detection of recurrence and thus the early administration of consolidation treatment resulting in a better prognosis.
American Psychological Association (APA)
Damak, Tarak& Chargui, Riadh& Ben Hassouna, Jamel& Hechiche, Monia& Rahal, Khaled. 2012. Results of Second-Look Laparotomy in Advanced Ovarian Cancer : One Single Center Experience. ISRN Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-503135
Modern Language Association (MLA)
Damak, Tarak…[et al.]. Results of Second-Look Laparotomy in Advanced Ovarian Cancer : One Single Center Experience. ISRN Obstetrics and Gynecology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-503135
American Medical Association (AMA)
Damak, Tarak& Chargui, Riadh& Ben Hassouna, Jamel& Hechiche, Monia& Rahal, Khaled. Results of Second-Look Laparotomy in Advanced Ovarian Cancer : One Single Center Experience. ISRN Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-503135
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503135