Methods to Assess the Protective Efficacy of Emollients against Climatic and Chemical Aggressors
Joint Authors
Lanctin, Marion
Roure, Romain
Bertin, Christiane
Nollent, Virginie
Source
Dermatology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Exposure to harsh environmental conditions, such as cold and dry climate and chemicals can have an abrasive effect on skin.
Skin care products containing ingredients that avert these noxious effects by reinforcement of the barrier function can be tested using in vivo models.
The objective is to use in vivo models to assess the efficacy of emollients in protecting skin against climatic and chemical insults.
A first model used a stream of cooled air to mimic cold wind.
A second used sodium lauryl sulfate (SLS) under patch as chemical aggressor.
In the model with simulated wind exposure, the untreated exposed area had a significant decrease in hydration.
In contrast, application of an emollient caused a significant increase in hydration that was maintained after wind exposure.
In the second model with SLS exposure, application of a barrier cream before SLS patch significantly reduced the dehydrating effect of SLS with a significant difference in variation between both areas.
Application of the cream reduced TEWL, indicative of a physical reinforcement of the skin barrier.
The two presented test methods, done under standardized conditions, can be used for evaluation of protective effect of emollient, by reinforcing the barrier function against experimentally induced skin dehydration.
American Psychological Association (APA)
Roure, Romain& Lanctin, Marion& Nollent, Virginie& Bertin, Christiane. 2012. Methods to Assess the Protective Efficacy of Emollients against Climatic and Chemical Aggressors. Dermatology Research and Practice،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-504505
Modern Language Association (MLA)
Roure, Romain…[et al.]. Methods to Assess the Protective Efficacy of Emollients against Climatic and Chemical Aggressors. Dermatology Research and Practice No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-504505
American Medical Association (AMA)
Roure, Romain& Lanctin, Marion& Nollent, Virginie& Bertin, Christiane. Methods to Assess the Protective Efficacy of Emollients against Climatic and Chemical Aggressors. Dermatology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-504505
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504505