Waldenstrom’s Macroglobulinemia and Peripheral Neuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes with a Bleeding Diathesis and Rash
Joint Authors
Haider, S.
Lucas, F.
Latif, T.
Hochhausler, A.
Abdel Karim, Nagla
Source
Case Reports in Oncological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-25
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We report a case of a 29-year-old male who presented with paraesthesia and skin lesions with excessive bleeding after skin biopsy leading to hematology consultation.
He was found to have prolonged partial thromboplastin time (PTT) and monoclonal gammopathy on serum protein electrophoresis (SPEP).
He experienced excessive bleeding leading to hospitalization after bone marrow biopsy and required blood transfusion.
He was diagnosed with Waldenstrom's Macroglobulinemia (WM), based on the presence of IgM-κ type monoclonal (M) protein and infiltration of lymphoplasmacytic cells identified in bone marrow aspirates.
He was noticed to have features of peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS syndrome).
This is a very rare case of WM with POEMS syndrome which responded to chemotherapy using bortezomib, steroids, and rituximab.
American Psychological Association (APA)
Haider, S.& Latif, T.& Hochhausler, A.& Lucas, F.& Abdel Karim, Nagla. 2013. Waldenstrom’s Macroglobulinemia and Peripheral Neuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes with a Bleeding Diathesis and Rash. Case Reports in Oncological Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-505774
Modern Language Association (MLA)
Haider, S.…[et al.]. Waldenstrom’s Macroglobulinemia and Peripheral Neuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes with a Bleeding Diathesis and Rash. Case Reports in Oncological Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-505774
American Medical Association (AMA)
Haider, S.& Latif, T.& Hochhausler, A.& Lucas, F.& Abdel Karim, Nagla. Waldenstrom’s Macroglobulinemia and Peripheral Neuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes with a Bleeding Diathesis and Rash. Case Reports in Oncological Medicine. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-505774
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505774
