Preparation and Characterization of Water-Soluble Chitosan Nanoparticles as Protein Delivery System
Joint Authors
Zang, Lin-quan
Zhang, Hong-liang
Wu, Si-hui
Tao, Yi
Su, Zheng-quan
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
The objective of this study was to investigate the potential of water soluble chitosan as a carrier in the preparation of protein-loaded nanoparticles.
Nanoparticles were prepared by ionotropic gelation of water-soluble chitosan (WSC) with sodium tripolyphosphate (TPP).
Bovine serum albumin (BSA) was applied as a model drug.
The size and morphology of the nanoparticles were investigated as a function of the preparation conditions.
The particles were spherical in shape and had a smooth surface.
The size range of the nanoparticles was between 100 and 400 nm.
Result of the in vitro studies showed that the WSC nanoparticles enhance and prolong the intestinal absorption of BSA.
These results also indicated that WSC nanoparticles were a potential protein delivery system.
American Psychological Association (APA)
Zhang, Hong-liang& Wu, Si-hui& Tao, Yi& Zang, Lin-quan& Su, Zheng-quan. 2009. Preparation and Characterization of Water-Soluble Chitosan Nanoparticles as Protein Delivery System. Journal of Nanomaterials،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-506509
Modern Language Association (MLA)
Zhang, Hong-liang…[et al.]. Preparation and Characterization of Water-Soluble Chitosan Nanoparticles as Protein Delivery System. Journal of Nanomaterials No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-506509
American Medical Association (AMA)
Zhang, Hong-liang& Wu, Si-hui& Tao, Yi& Zang, Lin-quan& Su, Zheng-quan. Preparation and Characterization of Water-Soluble Chitosan Nanoparticles as Protein Delivery System. Journal of Nanomaterials. 2009. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-506509
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506509
