The Involvement of a Polyphenol-Rich Extract of Black Chokeberry in Oxidative Stress on Experimental Arterial Hypertension
Joint Authors
Miron, Anca
Bădescu, Magda
Ciocoiu, Manuela
Badescu, Laurentiu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The aim of this study is to characterize the content of Aronia melanocarpa Elliott (black chokeberry) extract and also to estimate the influence of polyphenolic compounds contained in chokeberries on oxidative stress, on an L-NAME-induced experimental model of arterial hypertension.
The rat blood pressure values were recorded using a CODA Noninvasive Blood Pressure System.
HPLC/DAD coupled with ElectroSpray Ionization-Mass Spectrometry allowed identification of five phenolic compounds in berries ethanolic extract as follows: chlorogenic acid, kuromanin, rutin, hyperoside, and quercetin.
The serous activity of glutathione-peroxidase (GSH-Px) has significantly lower values in the hypertensive (AHT) group as compared to the group protected by polyphenols (AHT + P).
The total antioxidant capacity (TAC) values are lower in the AHT group and they are significantly higher in the AHT + P group.
All the measured blood pressure components revealed a biostatistically significant blood pressure drop between the AHT group and the AHT + P group.
The results reveal the normalization of the reduced glutathion (GSH) concentration as well as a considerable reduction in the malondialdehyde (MDA) serum concentration in the AHT + P group.
Ethanolic extract of black chokeberry fruits not only has a potential value as a prophylactic agent but also may function as a nutritional supplement in the management of arterial hypertension.
American Psychological Association (APA)
Ciocoiu, Manuela& Badescu, Laurentiu& Miron, Anca& Bădescu, Magda. 2013. The Involvement of a Polyphenol-Rich Extract of Black Chokeberry in Oxidative Stress on Experimental Arterial Hypertension. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-507532
Modern Language Association (MLA)
Ciocoiu, Manuela…[et al.]. The Involvement of a Polyphenol-Rich Extract of Black Chokeberry in Oxidative Stress on Experimental Arterial Hypertension. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-507532
American Medical Association (AMA)
Ciocoiu, Manuela& Badescu, Laurentiu& Miron, Anca& Bădescu, Magda. The Involvement of a Polyphenol-Rich Extract of Black Chokeberry in Oxidative Stress on Experimental Arterial Hypertension. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-507532
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507532