Plasmacytoid Melanoma of the Urinary Bladder and Lymph Nodes with Immunohistochemical Expression of Plasma Cell Markers Revealing Primary Esophageal Melanoma
Joint Authors
Sellami-Boudawara, Tahya
Charfi, Slim
Amouri, Ali
Ellouze, Sameh
Khabir, Abdelmajid
Mnif, Hela
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Plasmacytoid variant of melanoma is reported in only rare cases.
We present the case of a 54-years-old man admitted for enlarged lymph nodes in the lumbar region.
Initial diagnosis of plasmablastic lymphoma/plasma cell myeloma was considered.
At our institute, a bladder polyp was removed.
Microscopic exam demonstrated dense plasmacytoid cells infiltration with pigment deposits.
Immunohistochemical study showed strong expression of HMB45, Melan A, and vimentin.
There was focal positivity with S100 protein and CD138/syndecan-1.
The diagnosis of metastatic plasmacytoid melanoma was finally established.
Clinical exam revealed an esophageal melanoma with melanosis supporting its primary location.
Although rarely, melanoma especially plasmacytoid variant may express plasma cell markers which may lead to erroneous diagnosis of plasma cell proliferation.
Careful morphological examination for melanin pigment and the use of panel of melanocytic markers are helpful for diagnosis.
American Psychological Association (APA)
Charfi, Slim& Ellouze, Sameh& Mnif, Hela& Amouri, Ali& Khabir, Abdelmajid& Sellami-Boudawara, Tahya. 2012. Plasmacytoid Melanoma of the Urinary Bladder and Lymph Nodes with Immunohistochemical Expression of Plasma Cell Markers Revealing Primary Esophageal Melanoma. Case Reports in Pathology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-507832
Modern Language Association (MLA)
Charfi, Slim…[et al.]. Plasmacytoid Melanoma of the Urinary Bladder and Lymph Nodes with Immunohistochemical Expression of Plasma Cell Markers Revealing Primary Esophageal Melanoma. Case Reports in Pathology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-507832
American Medical Association (AMA)
Charfi, Slim& Ellouze, Sameh& Mnif, Hela& Amouri, Ali& Khabir, Abdelmajid& Sellami-Boudawara, Tahya. Plasmacytoid Melanoma of the Urinary Bladder and Lymph Nodes with Immunohistochemical Expression of Plasma Cell Markers Revealing Primary Esophageal Melanoma. Case Reports in Pathology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-507832
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507832