Does Varicocelectomy Improve Gonadal Function in Men with Hypogonadism and Infertility? Analysis of a Prospective Study
Joint Authors
Sathya Srini, Vasan
Belur Veerachari, Srinivas
Source
International Journal of Endocrinology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Varicocele in infertile males is associated with Leydig cell dysfunction and hypogonadism.
The effect of varicocelectomy on serum testosterone level is not yet established.
We analysed 200 heterosexual infertile men diagnosed to have clinical varicocele they were divided into two groups: group 1 (100 men) had microsurgical varicocelectomy, and group 2 (100 patients) underwent assisted reproduction procedures.
All participants had semen analysis, serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, and total testosterone (TT), measured both at recruitment time and 6 months later.
In group 1, the mean TT level increased significantly after varicocelectomy (1.644±0.029 to 2.461±0.0198 ng/dL, P<0.0001) and testicular size correlated with the mean change in TT (P=0.001).
No similar change was found in group 2.
Out of the 100 patients in group 1, 78 had postoperative normalization of TT unlike only 16 men in group 2.
American Psychological Association (APA)
Sathya Srini, Vasan& Belur Veerachari, Srinivas. 2011. Does Varicocelectomy Improve Gonadal Function in Men with Hypogonadism and Infertility? Analysis of a Prospective Study. International Journal of Endocrinology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-507846
Modern Language Association (MLA)
Sathya Srini, Vasan& Belur Veerachari, Srinivas. Does Varicocelectomy Improve Gonadal Function in Men with Hypogonadism and Infertility? Analysis of a Prospective Study. International Journal of Endocrinology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-507846
American Medical Association (AMA)
Sathya Srini, Vasan& Belur Veerachari, Srinivas. Does Varicocelectomy Improve Gonadal Function in Men with Hypogonadism and Infertility? Analysis of a Prospective Study. International Journal of Endocrinology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-507846
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507846