Understanding Postprandial Inflammation and Its Relationship to Lifestyle Behaviour and Metabolic Diseases
Joint Authors
Mamo, John C. L.
Proctor, Spencer D.
Cabezas, Manuel Castro
Klop, Boudewijn
Botham, Kathleen M.
Source
International Journal of Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-25
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Postprandial hyperlipidemia with accumulation of remnant lipoproteins is a common metabolic disturbance associated with atherosclerosis and vascular dysfunction, particularly during chronic disease states such as obesity, the metabolic syndrome and, diabetes.
Remnant lipoproteins become attached to the vascular wall, where they can penetrate intact endothelium causing foam cell formation.
Postprandial remnant lipoproteins can activate circulating leukocytes, upregulate the expression of endothelial adhesion molecules, facilitate adhesion and migration of inflammatory cells into the subendothelial space, and activate the complement system.
Since humans are postprandial most of the day, the continuous generation of remnants after each meal may be one of the triggers for the development of atherosclerosis.
Modulation of postprandial lipemia by lifestyle changes and pharmacological interventions could result in a further decrease of cardiovascular mortality and morbidity.
This paper will provide an update on current concepts concerning the relationship between postprandial lipemia, inflammation, vascular function, and therapeutic options.
American Psychological Association (APA)
Klop, Boudewijn& Proctor, Spencer D.& Mamo, John C. L.& Botham, Kathleen M.& Cabezas, Manuel Castro. 2011. Understanding Postprandial Inflammation and Its Relationship to Lifestyle Behaviour and Metabolic Diseases. International Journal of Vascular Medicine،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-510476
Modern Language Association (MLA)
Klop, Boudewijn…[et al.]. Understanding Postprandial Inflammation and Its Relationship to Lifestyle Behaviour and Metabolic Diseases. International Journal of Vascular Medicine No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-510476
American Medical Association (AMA)
Klop, Boudewijn& Proctor, Spencer D.& Mamo, John C. L.& Botham, Kathleen M.& Cabezas, Manuel Castro. Understanding Postprandial Inflammation and Its Relationship to Lifestyle Behaviour and Metabolic Diseases. International Journal of Vascular Medicine. 2011. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-510476
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-510476