Potential Uses, Limitations, and Basic Procedures of Micronuclei and Nuclear Abnormalities in Buccal Cells
Joint Authors
Nava, Arnulfo
Torres-Bugarín, Olivia
Zavala-Cerna, María Guadalupe
Ramos-Ibarra, María Luisa
Flores-García, Aurelio
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-04
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The use of biomarkers as tools to evaluate genotoxicity is increasing recently.
Methods that have been used previously to evaluate genomic instability are frequently expensive, complicated, and invasive.
The micronuclei (MN) and nuclear abnormalities (NA) technique in buccal cells offers a great opportunity to evaluate in a clear and precise way the appearance of genetic damage whether it is present as a consequence of occupational or environmental risk.
This technique is reliable, fast, relatively simple, cheap, and minimally invasive and causes no pain.
So, it is well accepted by patients; it can also be used to assess the genotoxic effect derived from drug use or as a result of having a chronic disease.
Furthermore the beneficial effects derived from changes in life style or taking additional supplements can also be evaluated.
In the present paper, we aim to focus on the explanation of MN test and its usefulness as a biomarker; we further give details about procedures to perform and interpret the results of the test and review some factors that could have an influence on the results of the technique.
American Psychological Association (APA)
Torres-Bugarín, Olivia& Zavala-Cerna, María Guadalupe& Nava, Arnulfo& Flores-García, Aurelio& Ramos-Ibarra, María Luisa. 2014. Potential Uses, Limitations, and Basic Procedures of Micronuclei and Nuclear Abnormalities in Buccal Cells. Disease Markers،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-511275
Modern Language Association (MLA)
Torres-Bugarín, Olivia…[et al.]. Potential Uses, Limitations, and Basic Procedures of Micronuclei and Nuclear Abnormalities in Buccal Cells. Disease Markers No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-511275
American Medical Association (AMA)
Torres-Bugarín, Olivia& Zavala-Cerna, María Guadalupe& Nava, Arnulfo& Flores-García, Aurelio& Ramos-Ibarra, María Luisa. Potential Uses, Limitations, and Basic Procedures of Micronuclei and Nuclear Abnormalities in Buccal Cells. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-511275
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511275