Effect of Quercetin on Haematobiochemical and Histological Changes in the Liver of Polychlorined Biphenyls-Induced Adult Male Wistar Rats
Joint Authors
Ahmad Bhat, Firdous
Krishnamoorthy, Gunasekaran
Bavithra, Senthamilselvan
Selvakumar, Kandaswamy
Suganya, Sekaran
Arunakaran, Jagadeesan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-01
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Polychlorinated biphenyls exposure damages the rat liver cells.
Hematological parameters such as hemoglobin, packed cell volume, red-blood cells, white-blood cells, neutrophils, platelet counts, and RBC indices were significantly decreased.
Polymorphs, eosinophil counts, and erythrocyte sedimentation rate were significantly increased.
Serum liver enzymes such as aspartate transaminase, alanine transaminase, alkaline phosphatase, and gamma-glutamyl transferase were increased by PCBs treatment.
Serum lipid profiles such as cholesterol, triglycerides, low-density lipoproteins and very-low-density lipoproteins were increased in PCBs-treated rats.
High-density lipoprotein, total protein, albumin, globulin levels, and albumin/globulin ratio were also decreased after PCB exposure.
Then levels of sodium, potassium, chloride, and bicarbonate were also altered.
Serum glucose levels were increased along with total bilirubin after PCBs exposure.
Simultaneous quercetin supplementation significantly protected the PCBs-induced changes of hematobiochemical parameters.
Thus, quercetin shows a protective role against PCBs-induced alterations in the hematological and biochemical parameters.
American Psychological Association (APA)
Selvakumar, Kandaswamy& Bavithra, Senthamilselvan& Suganya, Sekaran& Ahmad Bhat, Firdous& Krishnamoorthy, Gunasekaran& Arunakaran, Jagadeesan. 2012. Effect of Quercetin on Haematobiochemical and Histological Changes in the Liver of Polychlorined Biphenyls-Induced Adult Male Wistar Rats. Journal of Biomarkers،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-511559
Modern Language Association (MLA)
Selvakumar, Kandaswamy…[et al.]. Effect of Quercetin on Haematobiochemical and Histological Changes in the Liver of Polychlorined Biphenyls-Induced Adult Male Wistar Rats. Journal of Biomarkers No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-511559
American Medical Association (AMA)
Selvakumar, Kandaswamy& Bavithra, Senthamilselvan& Suganya, Sekaran& Ahmad Bhat, Firdous& Krishnamoorthy, Gunasekaran& Arunakaran, Jagadeesan. Effect of Quercetin on Haematobiochemical and Histological Changes in the Liver of Polychlorined Biphenyls-Induced Adult Male Wistar Rats. Journal of Biomarkers. 2012. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-511559
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-511559