Acromegaloid Facial Appearance : Case Report and Literature Review
Joint Authors
Khosla, Shikha
Ghazi, Adline
Becker, Kenneth
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Pseudoacromegaly is characterized by an acromegalic appearance without any abnormality of growth hormone function.
It may be caused by several congenital and acquired conditions.
One such condition is the acromegaloid facial appearance (AFA) syndrome.
This condition has been described in approximately eight cases/families.
It encompasses a spectrum of acromegaloid physical findings, normal growth hormone (GH) and insulin-like growth factor one (IGF-1) levels, and variable mode of inheritance.
The most common physical findings are coarse facies, bulbous nose, and thickened lips.
We present a case and a review of the literature on this illness.
The patient is a 57-year-old woman who was referred to the endocrinology division for evaluation of suspected acromegaly.
She had an acromegaloid appearance since birth as well as a terminal hypertrichosis.
Her endocrine laboratory evaluation and chromosomal analyses were normal.
AFA needs to be considered when evaluating any patient with pseudoacromegaly.
Additional cases/families need to be identified in order to better understand the clinical spectrum, clinical implications, and mode of inheritance of AFA.
American Psychological Association (APA)
Ghazi, Adline& Khosla, Shikha& Becker, Kenneth. 2013. Acromegaloid Facial Appearance : Case Report and Literature Review. Case Reports in Endocrinology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-512342
Modern Language Association (MLA)
Ghazi, Adline…[et al.]. Acromegaloid Facial Appearance : Case Report and Literature Review. Case Reports in Endocrinology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-512342
American Medical Association (AMA)
Ghazi, Adline& Khosla, Shikha& Becker, Kenneth. Acromegaloid Facial Appearance : Case Report and Literature Review. Case Reports in Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-512342
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-512342