مستوى مضادات الأكسدة في مصل دم مرضى ارتفاع الكولسترول في الدم

Abstract EN

This study included evaluation the relationship between cholesterol and antioxidants level in the human with hypercholesterolemia.

Blood of 33 samples were collected from patients with hypercholesterolemia 18 male and 15 female with age ranging between (42–60 )year .

20 samples of blood were also collected from human with normal cholesterol (10 male , 10 female), this group considered the control group.

Cholesterol, Vitamin C, Glutathione, SOD activity, peroxy nitrite, and albumin levels, were measured in the serum of both groups.

The statistical results showed a significant increase (p < 0.05) in the SOD activity and peroxy nitrite concentration in the human with hypercholesterolemia for both sex compared with the control group, while insignificant increase was showed in the albumin levels in the hypercholesterolemia patients compared with control group.

The results also showed a significant decrease (p < 0.05) in vitamin C and glutathione levels in the patients with hypercholesterolemia for both sex compared with control group.

This study demonstrated that there was a relationship between antioxidants levels and hypercholesterolemia patients, male and female include (Vitamin C, Glutathione, Peroxy nitrite, Superoxide Dismutas enzyme).