Nebulized versus intravenous fentanyl for postoperative analgesia after unilateral arthroscopic anterior cruciate ligament reconstruction surgery : a prospective, randomized, comparative trial
Joint Authors
al-Rabii, Muhammad A. I.
Afifi, Ihab E.
Abd al-Hamid, Ahmad M.
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 8, Issue 3 (30 Sep. 2015), pp.316-319, 4 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2015-09-30
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Topics
Abstract EN
Objectives This study aimed to compare the effect of nebulized fentanyl with intravenous fentanyl for postoperative analgesia after unilateral arthroscopic anterior cruciate ligament reconstruction surgery.
Patients and methods A total of 87 patients scheduled for unilateral arthroscopic anterior cruciate ligament reconstruction surgery under regional anesthesia were enrolled in the study and were randomly allocated into two groups.
Group IV included 42 patients who received 2 μg/kg of fentanyl intravenously, and Group N included 45 patients who received 4 μg/kg of fentanyl nebulization using a standard ventimask.
Both groups received the analgesic drug through either intravenously or nebulization route whenever the patient reported pain for the fi rst time in the postanesthesia care unit that was of a score greater than 4 on the visual analog scale.
Observations were made for the onset and duration of analgesia, number of patients who were not relieved of pain even 15 min after analgesia administration, level of sedation using the Ramsay sedation scale, and side effects.
Results Both groups were similar in terms of demographic characteristics and duration of surgery.
The onset of analgesia was signifi cantly delayed in group N in comparison with group IV, whereas the duration of analgesia was signifi cantly longer in group N in comparison with group IV.
In group IV, the Ramsay sedation score was the maximum at 5 min.
In group N, there was a slow rise in the sedation score, but it was always less than that in group IV.
Side effects in group N were less compared with group IV, and the number of patients who developed bradycardia was signifi cantly higher in group IV.
Conclusion This study showed that nebulization with fentanyl is a good alternative to intravenous fentanyl for adequate postoperative pain relief with fewer side effects.
American Psychological Association (APA)
Abd al-Hamid, Ahmad M.& al-Rabii, Muhammad A. I.& Afifi, Ihab E.. 2015. Nebulized versus intravenous fentanyl for postoperative analgesia after unilateral arthroscopic anterior cruciate ligament reconstruction surgery : a prospective, randomized, comparative trial. Ain Shams Journal of Anesthesiology،Vol. 8, no. 3, pp.316-319.
https://search.emarefa.net/detail/BIM-650195
Modern Language Association (MLA)
Abd al-Hamid, Ahmad M.…[et al.]. Nebulized versus intravenous fentanyl for postoperative analgesia after unilateral arthroscopic anterior cruciate ligament reconstruction surgery : a prospective, randomized, comparative trial. Ain Shams Journal of Anesthesiology Vol. 8, no. 3 (Jul. / Sep. 2015), pp.316-319.
https://search.emarefa.net/detail/BIM-650195
American Medical Association (AMA)
Abd al-Hamid, Ahmad M.& al-Rabii, Muhammad A. I.& Afifi, Ihab E.. Nebulized versus intravenous fentanyl for postoperative analgesia after unilateral arthroscopic anterior cruciate ligament reconstruction surgery : a prospective, randomized, comparative trial. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 3, pp.316-319.
https://search.emarefa.net/detail/BIM-650195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 319
Record ID
BIM-650195