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دراسة التأثير المضاد للالتصاق الجرثومي للمركبات المستخدمة في معالجة مرض القثاطر البولية تجريبيا
Other Title(s)
Empirical study of anti-adherent effect of chemotherapeutic compounds used in the treatment of patients with urethral catheters
Joint Authors
Source
Issue
Vol. 6, Issue 9 (30 Apr. 2013), pp.33-48, 16 p.
Publisher
Syrian Clinical Laboratory Association
Publication Date
2013-04-30
Country of Publication
Syria
No. of Pages
16
Main Subjects
Topics
- Microbiology
- Urinary system
- Diseases
- Fever
- Chemotherapy
- Drugs
- Therapeutics
- Antibiotics
- Bacteria
- Penicillin
- Biomedical materials
Abstract EN
Sub-minimum inhibitory concentrations (sub-MICs) of antibiotics, although not able to kill bacteria, can modify their physicochemical characteristics and the architecture their outermost surface, and may interfere with some bacterial functions such as adherence.
In this study the effects of sub-MIC (1/2, 1/4, 1/8) of Compounds normally used in treatment patients with urethral catheters were evaluated.
The study was done using Amikacin, Levofloxacin, Ceftriaxon and Nitrofurantoin as urethral antiseptic, and sodium Diclofinac, a common analgesic used in such cases.
The effect of these compounds on bacterial adhesion of five strains, including Klebsiella pneumonia, Escherichia coli, Pseudomonas aeruginosa, was studied.
The strains were taken from patients with indwelling urethral catheters.
our results revealed that Amikacin, Levofloxacin and Ceftriaxon were of good effect in reducing bacterial adhesion for susceptible and intermediate susceptible strains, however Nitrofurantoin was less effect even on susceptible strains.
In resistant strains, Levofloxacin was the most effective antibiotic in reducing bacterial adhesion, while the other antibiotics and Diclofinac were ineffective
American Psychological Association (APA)
الحمش، مهند والمعموري، مصطفى. 2013. دراسة التأثير المضاد للالتصاق الجرثومي للمركبات المستخدمة في معالجة مرض القثاطر البولية تجريبيا. مجلة التشخيص المخبري،مج. 6، ع. 9، ص ص. 33-48.
https://search.emarefa.net/detail/BIM-656760
Modern Language Association (MLA)
الحمش، مهند والمعموري، مصطفى. دراسة التأثير المضاد للالتصاق الجرثومي للمركبات المستخدمة في معالجة مرض القثاطر البولية تجريبيا. مجلة التشخيص المخبري مج. 6، ع. 9 (نيسان 2013)، ص ص. 33-48.
https://search.emarefa.net/detail/BIM-656760
American Medical Association (AMA)
الحمش، مهند والمعموري، مصطفى. دراسة التأثير المضاد للالتصاق الجرثومي للمركبات المستخدمة في معالجة مرض القثاطر البولية تجريبيا. مجلة التشخيص المخبري. 2013. مج. 6، ع. 9، ص ص. 33-48.
https://search.emarefa.net/detail/BIM-656760
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 44-48
Record ID
BIM-656760