علاقة الدراسة الشكلية للنطاف مع نتائج الحمل بالإمناء ضمن الرحم

Abstract EN

One of the causes of infertility is due to male factors (may be due to disorders in the number of spermatozoa, sperm motility or sperm morphology).

Intrauterine insemination (IUI) is routinely used to help couples with male factor infertility.

The criteria used to evaluate semen quality include sperm concentration, sperm motility and the percentage of sperm with normal morphology.

Several studies have been done on motility and sperm concentration, but few studies have been done on sperm morphology.

So the attempt was made to study the relationship between sperm morphology and IUI outcome, where the percentages of normal sperm in this study≥ 14, and < 14%.

Study performed on patients coming to orient hospital of fertilization, infertility treatment and IVF.

After ovulation induction for wife, semen samples were collected from the male (100 patients), and left in sterile tubes and then treated with swim up before performing IUI.

Sperm concentration, motility and morphology were evaluated according world health organization criteria (WHO, 2010), where only samples containing 1 million motile sperm per ml, with normal progressive motility (a+b ≥ 32%), have been inseminated for only studying the sperm morphology effect.

Statistical analysis was done by MEDCALC program (version 12) Chi-square test, and the result was significant when p–value < 0.05.

Results: Out of 46 patients, (normal sperm morphology < 14 %) IUIs were successful in 14 patients (30.4%), and out of 54 patients (normal sperm morphology ≥ 14%) IUIs were successful in 14patients (25.9%),the difference being not statistically significant (p-value>0.05).

As a Conclusion, It seems that normal sperm morphology ≥14% is not an important or effective factor in IUI outcomes, so our results suggest the use of IUI when normal sperm morphology in semen analysis < 14% before moving on to use more costly and complicated techniques as the in vitro fertilization (IVF) and the intra cytoplasmic sperm injection (ICSI).