Malignant hypertension-associated thrombotic microangiopathy following cocaine use
Joint Authors
Lamia, Rais
Raniya, Khidr
Krid, Madihah
al-Ati, Zahrah
Biji, Sumayyah
Zouaghi, Karim
Bin Fatimah, Layla
Bin Musa, Fatimah
Bin Hamidah, Fathi
Samawi, Wided
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 27, Issue 1 (29 Feb. 2016), pp.153-156, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2016-02-29
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
- Case studies
- Hypertension
- Anaesthesia
- Complications(Medicine)
- Kidney failure
- Cocaine
- Thrombotic microangiopathy
Abstract EN
Cocaine is one of the most commonly used illicit drugs with distribution and consumption throughout the world.
Acute renal failure associated with rhabdomyolysis, direct vasoconstriction and hemodynamic alteration is well described in patients with cocaine intoxication.
Cocaine use is associated with high blood pressure and may rarely induce malignant hypertension associated with thrombotic microangiopathy.
We report the case of a patient who developed malignant hypertension associated with thrombotic microangiopathy after chronic consumption of cocaine.
A kidney biopsy revealed thrombotic microangiopathy with fibrinoid necrosis of arterioles and glomerular tufts.
He required dialysis sessions.
Cocaine-mediated endothelial injury and platelet activation may play important pathogenetic roles in cocaine abusers who develop malignant hypertension associated with thrombotic microangiopathy.
Clinicians need to be aware of this rare feature of cocaine intoxication.
American Psychological Association (APA)
Lamia, Rais& al-Ati, Zahrah& Bin Fatimah, Layla& Zouaghi, Karim& Samawi, Wided& Biji, Sumayyah…[et al.]. 2016. Malignant hypertension-associated thrombotic microangiopathy following cocaine use. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 1, pp.153-156.
https://search.emarefa.net/detail/BIM-669198
Modern Language Association (MLA)
Lamia, Rais…[et al.]. Malignant hypertension-associated thrombotic microangiopathy following cocaine use. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 1 (Jan. / Feb. 2016), pp.153-156.
https://search.emarefa.net/detail/BIM-669198
American Medical Association (AMA)
Lamia, Rais& al-Ati, Zahrah& Bin Fatimah, Layla& Zouaghi, Karim& Samawi, Wided& Biji, Sumayyah…[et al.]. Malignant hypertension-associated thrombotic microangiopathy following cocaine use. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 1, pp.153-156.
https://search.emarefa.net/detail/BIM-669198
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 156
Record ID
BIM-669198