Superficial urinary bladder cancer : histopathological findings, recurrence rate after transurethral resection and association with upper urinary tract urothelial cancer : retrospective analysis

Abstract EN

Objective: To assess different histopathological types of superficial urinary bladder cancer, their recurrence incidence and correlation with upper urinary tract urothelial cancer.

Methods: This retrospective study included 84 patients, of both genders; of different age groups and with histpathological diagnosis of superficial urothelial carcinoma at Prince Hussein bin Abdullah the second center for urology and organ transplant and at Prince Iman center for laboratory research, King Hussein medical centre, Amman, Jordan, during the period March 2010-May 2014.

Transurethral resection of tumor was performed in all subjects with tumor grading and staging.

Cystoscopic follow up was performed to record incidence of recurrence in all subjects.

Results: The mean age of patients was 61 years; with male percentage (84.5%).Successful transurethral resection of tumor in first trial was achievable in 68 patients (80.95%).

Multiple tumors were recorded in 35 patients (41.7%).Total recurrence incidence was recorded in 75% of patients.

Subjects with TaG3 experienced delayed recurrence frequency of 22.2% with good recurrence- free period, while T1G3 subjects had less and early recurrence incidence of 15.9%.

Conclusion: Early recurrence was recorded with tumor limited to sub epithelium (T1), while late recurrence was recorded with urothelium confined disease (Ta).