Spectrophotometric determination of zinc in pharmaceutical preparations by using a new synthesized reagent [4, 5-diphenyl-2-((1e)-(4-(1-(2 phenylhydrazono) ethyl) phenyl) diazenyl)-4h-imidazole]
Joint Authors
Muhammad, Ali F.
Baqir, Sadiq Jafar
Source
Iraqi National Journal of Chemistry
Issue
Vol. 15, Issue 3 (30 Sep. 2015), pp.271-283, 13 p.
Publisher
University of Babylon College of Sciences
Publication Date
2015-09-30
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Abstract EN
A simple , rapid, sensitive and new spectrophotometric method to estimate zinc in pharmaceutical preparations is described.
The method depends on the reaction between zinc and the new synthesized reagent [4,5-diphenyl-2-((1E)-(4-(1-(2-phenylhydrazono)ethyl)phenyl)diazenyl)-4H-imidazole] (DPHEDPI ) to form a reddish-pink complex at pH 7.5 with a mole ratio (M:L)of (1:2), the complex exhibits a maximum absorbance at 520 nm with molar absorptivity coefficient (Ɛ) of 4.4*102 L.mol-1 cm-1.
Beer’s law is obeyed in the range of (0.5–27) ppm for zinc with correlation coefficient of (0.9996) ,and the stability constant was found to be 1*10 12 L.mol-1.
The relative standard deviation for seven replicate measurements, relative error and recovery values of this method were found to be 0.0015 % , -0.778%, and 99.22% respectively.
Finally, this proposed method was applied for the determination of zinc in the zinc sulphate capsules drug and the results were compared with atomic absorption method
American Psychological Association (APA)
Muhammad, Ali F.& Baqir, Sadiq Jafar. 2015. Spectrophotometric determination of zinc in pharmaceutical preparations by using a new synthesized reagent [4, 5-diphenyl-2-((1e)-(4-(1-(2 phenylhydrazono) ethyl) phenyl) diazenyl)-4h-imidazole]. Iraqi National Journal of Chemistry،Vol. 15, no. 3, pp.271-283.
https://search.emarefa.net/detail/BIM-708560
Modern Language Association (MLA)
Muhammad, Ali F.& Baqir, Sadiq Jafar. Spectrophotometric determination of zinc in pharmaceutical preparations by using a new synthesized reagent [4, 5-diphenyl-2-((1e)-(4-(1-(2 phenylhydrazono) ethyl) phenyl) diazenyl)-4h-imidazole]. Iraqi National Journal of Chemistry Vol. 15, no. 3 (2015), pp.271-283.
https://search.emarefa.net/detail/BIM-708560
American Medical Association (AMA)
Muhammad, Ali F.& Baqir, Sadiq Jafar. Spectrophotometric determination of zinc in pharmaceutical preparations by using a new synthesized reagent [4, 5-diphenyl-2-((1e)-(4-(1-(2 phenylhydrazono) ethyl) phenyl) diazenyl)-4h-imidazole]. Iraqi National Journal of Chemistry. 2015. Vol. 15, no. 3, pp.271-283.
https://search.emarefa.net/detail/BIM-708560
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 282-283
Record ID
BIM-708560