Adsorption of cefixime on to Iraqi bentonite

Abstract EN

In this study the adsorption of cefixime on to selected Iraqi clay bentonite.

The aim of this study is to search for selective active surface in adsorption of the drug and to act as physical antidotes in treatment of poisoning if the drug is taken in quantities higher than the recommended dosages.

Quantitative estimation of the drug adsorption has been done by utilizing the technique of UV spectrophotometry in λmax (273) nm at different conditions of temperature (25, 37, 45) ˚C found the adsorption decrease with increase the temperature.

Study of clay weight of bentonite (0.1-1.5) gm found the adsorption increase with increase of clay weight, study effect of pH (1.2, 3, 5, 7) on adsorption of bentonite found the optimum adsorption at (pH = 5).

Finally effect of ionic strength on adsorption used NaCl solution (0.1-0.3) M found decrease with increase of ionic strength.

The results of adsorption isotherms fitted with freundlich isotherm-