دراسة مستويات الإندوتيلين-1 المصلية لدى مرضى فشل القلب
Other Title(s)
Serum levels of endothelin-1in patients with heart failure
Joint Authors
Source
Issue
Vol. 5, Issue 10 (31 Jan. 2011), pp.1-6, 6 p.
Publisher
Syrian Clinical Laboratory Association
Publication Date
2011-01-31
Country of Publication
Syria
No. of Pages
6
Main Subjects
Abstract EN
Endothelin-1 is a 21 amino acid peptide, and is the most potent vasoconstrictor, generated by vascular endothelial cells in response to a variety of chemical and mechanical signals.
Endothelin-1 contributes to the pathophysiology of conditions associated with sustained vasoconstriction, such as hypertension and heart failure.
Serum levels of endothelin-1 were measured by Enzyme Immunoassy in 137 subjects (27 normal subjects, 110 heart failure patients, who were clinically classified according to the New York Heart Association (NYHA) classification to NYHA II (31 patients), NYHA III (49 patients), and NYHA IV (30 patients).
Serum levels of Endothelin-1 were found to be significantly higher in heart failure patients compared with normal subjects, P value was <0.05, also Serum levels of Endothelin-1 were significantly associated with the severity of heart failure.
Our study elucidates that the serum levels of endothelin-1 are elevated in patients with heart failure and are associated with the progression of the disease, so routine serum endothelin-1 determination provides important prognostic information in heart failure
American Psychological Association (APA)
شربا، لمى والشماع، سحر. 2011. دراسة مستويات الإندوتيلين-1 المصلية لدى مرضى فشل القلب. مجلة التشخيص المخبري،مج. 5، ع. 10، ص ص. 1-6.
https://search.emarefa.net/detail/BIM-710159
Modern Language Association (MLA)
شربا، لمى والشماع، سحر. دراسة مستويات الإندوتيلين-1 المصلية لدى مرضى فشل القلب. مجلة التشخيص المخبري مج. 5، ع. 10 (كانون الثاني 2011)، ص ص. 1-6.
https://search.emarefa.net/detail/BIM-710159
American Medical Association (AMA)
شربا، لمى والشماع، سحر. دراسة مستويات الإندوتيلين-1 المصلية لدى مرضى فشل القلب. مجلة التشخيص المخبري. 2011. مج. 5، ع. 10، ص ص. 1-6.
https://search.emarefa.net/detail/BIM-710159
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية
Record ID
BIM-710159