Statin-associated muscle adverse events : update for clinicians
Other Title(s)
الأثار الجانبية المرتبطة بالعضلات لأدوية الستاتين : تحديث للأطباء السريرين
Joint Authors
al-Muhaysin, Maha
Ignaszewski, Martha J.
Ignaszewski, Andrew P.
Frohlich, Jiri
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 16, Issue 4 (30 Nov. 2016), pp.406-415, 10 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2016-11-30
Country of Publication
Oman
No. of Pages
10
Main Subjects
Topics
Abstract EN
Statins are potent medications which reduce low-density lipoprotein cholesterol (LDL-C) levels.
Their efficacy in cardiovascular risk reduction is well established and indications for their use are expanding.
While statins are generally well tolerated and safe, adverse events are relatively common, particularly statinassociated muscle adverse events (SaMAEs), which are the most frequently encountered type of adverse event.
Recent guidelines and guideline updates on SaMAEs and statin intolerance have included revised definitions of SaMAEs, incorporating new evidence on their pathogenesis and management.
As SaMAEs emerge as a therapeutic challenge, it is important for physicians to be aware of updates on management strategies to ensure better patient outcomes.
The majority of patients who are considered statin-intolerant can nevertheless tolerate some forms of statin herapy and successfully achieve optimal LDL-C levels.
This review article discusses the recent classification of SaMAEs with emphasis on pathogenesis and management strategies.
American Psychological Association (APA)
al-Muhaysin, Maha& Ignaszewski, Martha J.& Frohlich, Jiri& Ignaszewski, Andrew P.. 2016. Statin-associated muscle adverse events : update for clinicians. Sultan Qaboos University Medical Journal،Vol. 16, no. 4, pp.406-415.
https://search.emarefa.net/detail/BIM-721271
Modern Language Association (MLA)
al-Muhaysin, Maha…[et al.]. Statin-associated muscle adverse events : update for clinicians. Sultan Qaboos University Medical Journal Vol. 16, no. 4 (Nov. 2016), pp.406-415.
https://search.emarefa.net/detail/BIM-721271
American Medical Association (AMA)
al-Muhaysin, Maha& Ignaszewski, Martha J.& Frohlich, Jiri& Ignaszewski, Andrew P.. Statin-associated muscle adverse events : update for clinicians. Sultan Qaboos University Medical Journal. 2016. Vol. 16, no. 4, pp.406-415.
https://search.emarefa.net/detail/BIM-721271
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 413-415
Record ID
BIM-721271