اصطناع و دراسة بنية 3a-هيدروكسي-1-اتيل-3a-متيل-6e (2-هيدروكسي فنيل)‎-بيبيريدون أوكسيم-4 على أساس المماكب الفراغي الجديد 3a-هيدروكسي 3e-متيل-6e (2 بنزيلوكسي فنيل)‎ بيبيريدون-4

Abstract EN

The goal of this work is the synthesis of new piperidone heterocyclic derivatives with biological importance.These new compounds were geometrical isomers of other similar compounds we had synthesized in the previous study, and we studied a systematic method of synthesis of these compounds and identification of their structure and physical properties.

We obtained 1 - ethyl - 3a - hydroxy - 3e - methyl -6- (2-benzeyloxyphenyl) piperidone-4 (III).

We synthesized the derivatives of: 1α,8β- diacetoxy-6- ethyl -8α- methyl-2-oxa-6- aza-3,4-benzobicyclo [3,3,1] nonane (V), and 3a-hydroxy-1-ethyl-3e-methyl-6e (2-hydroxyphenyl) piperidone oxime.

The infrared spectrum IR, nuclear magnetic resonance 1 H-NMR spectroscopy and MS of these compounds were studied and we suggested the reactions mechanisms of the synthesized compounds.