استقصاء التعدد الشكلي (BsmI و ApaI) لجين مستقبل الفيتامين D لدى مرضى الربو
Other Title(s)
Investigation of vitamin d receptor gene (VDR) polymorphisms (ApaI, BsmI) in asthmatic patients
Joint Authors
Source
Issue
Vol. 8, Issue 1-2 (31 Jul. 2016), pp.39-46, 8 p.
Publisher
Syrian Clinical Laboratory Association
Publication Date
2016-07-31
Country of Publication
Syria
No. of Pages
8
Main Subjects
Topics
Abstract EN
Asthma is one of the common chronic diseases of airways; it is a complex disease with both genetic and environmental risk factors.
Asthma is caused by multiple interacting genes, some having a protective effect and others contributing to the disease pathogenesis.
Genome scans for asthma have identified suggestive or significant linkages on different chromosomes, including chromosome 12, region q13–23, housing the vitamin D receptor (VDR) gene.
This study aimed to investigate an association between BsmI and ApaI polymorphisms and the genetic susceptibility to asthma in Syrian population.
50 asthmatic patients and 50 controls were enrolled in this study; PCR-RFLP was performed to examine polymorphisms in the VDR gene.
Our results showed a statistically significant association of the BsmI polymorphism of the VDR and the asthma when comparing healthy controls to asthmatic patients (P value = 0.01, OR: 2.44, 95% CI: 1.38, 4.32).
American Psychological Association (APA)
الدرة، هيثم وحداد، شادن. 2016. استقصاء التعدد الشكلي (BsmI و ApaI) لجين مستقبل الفيتامين D لدى مرضى الربو. مجلة التشخيص المخبري،مج. 8، ع. 1-2، ص ص. 39-46.
https://search.emarefa.net/detail/BIM-746619
Modern Language Association (MLA)
الدرة، هيثم وحداد، شادن. استقصاء التعدد الشكلي (BsmI و ApaI) لجين مستقبل الفيتامين D لدى مرضى الربو. مجلة التشخيص المخبري مج. 8، ع. 1-2 (تموز 2016)، ص ص. 39-46.
https://search.emarefa.net/detail/BIM-746619
American Medical Association (AMA)
الدرة، هيثم وحداد، شادن. استقصاء التعدد الشكلي (BsmI و ApaI) لجين مستقبل الفيتامين D لدى مرضى الربو. مجلة التشخيص المخبري. 2016. مج. 8، ع. 1-2، ص ص. 39-46.
https://search.emarefa.net/detail/BIM-746619
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 45-46
Record ID
BIM-746619