التغيرات المرضية المحدثة تجريبيا بسموم الأفلا في أكباد فروج اللحم

Abstract EN

This study was conducted to evaluate the effect of Aflatoxin in different concentrations and at different periods gross and histopathological changes in liver of one-day-old broiler chicks (Ross 308), Broiler chicks were randomly assigned to five group(each with 30 chicks), They fed Aflatoxin at 4 different levels(0.5,1.0,1.5 and 2.0 mg/ kg feed), for 42 days, The results showed their intensity were positively correlated with the levels and period of Aflatoxins feed to Broilers .

The gross changes were characterized by paleness, enlargement and change in Liver color, ecchymotic hemorrhage under the liver capsule, The histopathological changes were characterized by fatty changes in the liver , bile duct Proliferation, inflammatory cells infiltration in the Preportal areas .

It was concluded from this study that Aflatoxins had accumulative effect in broiler chicks, and that the liver was the target organ and the most affected organ grossly and histopathologically .