Effect of probiotic supplementation on blood pressure of females with gestational diabetes mellitus : a randomized double blind controlled clinical trial
Joint Authors
Jahanjou, Fatimah
Zadeh, Fatimah Abbas Ali
Zadeh, Nasir Agha Muhammad
Abbasi, Mihran Misgari
Dolatkhah, Nida
Hajifaraji, Majid
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 19, Issue 6 (30 Jun. 2017), pp.1-10, 10 p.
Publisher
Publication Date
2017-06-30
Country of Publication
United Arab Emirates
No. of Pages
10
Main Subjects
Topics
- Pregnancy
- Patients
- Therapeutics
- Diabetes
- Blood pressure
- Complications(Medicine)
- Dietary supplements
- Females
Abstract EN
Background : Despite progress in the control and treatment of gestational diabetes mellitus (GDM) in pregnant females, these patients remain at risk of disease complications.
Objectives : the present study aimed at investigating the effect of probiotic supplements on Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) in pregnant females diagnosed with GDM.
Methods : this randomized double-blind, placebo-controlled trial randomly assigned 64 pregnant females with GDM, recruited through convenience sampling, to either a group receiving a probiotic capsule (n = 32) or a group receiving a placebo (n = 32) for 8 weeks in Tabriz, Iran, during the spring and summer months of 2014.
Their blood pressure was measured at baseline and at 2-week intervals, up to 8 weeks.
Results: A total of 56 subjects completed the study.
There was no significant difference in SBP in the probiotic group at any time compared with that at onset, yet, SBP increased significantly in the placebo group.
The declining trend of DBP was evident in the probiotic group at 2 weeks and continued to the end of the study; however, DBP had increased slightly by week 6 in the placebo group.
There were significant differences between the probiotic and placebo groups at 6 and 8 weeks, respectively, for SBP (104.828 (2.051) mmHg vs.
112.963 (2.126) mmHg; P = 0.008) and (106.552 (1.845) mmHg vs.
115.185 (1.912) mmHg; P = 0.002) and for DBP (62.414 (1.353) mmHg vs.
70.741 (1.402) mmHg; P < 0.001) and (60.690 (1.540) mmHg vs.
71.296 (1.596) mmHg; P < 0.0010).
Conclusions : the results demonstrated that consumption of probiotic supplements for 8 weeks prevented an increase in SBP and decreased DBP in pregnant females diagnosed with GDM.
American Psychological Association (APA)
Hajifaraji, Majid& Jahanjou, Fatimah& Zadeh, Fatimah Abbas Ali& Zadeh, Nasir Agha Muhammad& Abbasi, Mihran Misgari& Dolatkhah, Nida. 2017. Effect of probiotic supplementation on blood pressure of females with gestational diabetes mellitus : a randomized double blind controlled clinical trial. Iranian Red Crescent Medical Journal،Vol. 19, no. 6, pp.1-10.
https://search.emarefa.net/detail/BIM-767670
Modern Language Association (MLA)
Hajifaraji, Majid…[et al.]. Effect of probiotic supplementation on blood pressure of females with gestational diabetes mellitus : a randomized double blind controlled clinical trial. Iranian Red Crescent Medical Journal Vol. 19, no. 6 (Jun. 2017), pp.1-10.
https://search.emarefa.net/detail/BIM-767670
American Medical Association (AMA)
Hajifaraji, Majid& Jahanjou, Fatimah& Zadeh, Fatimah Abbas Ali& Zadeh, Nasir Agha Muhammad& Abbasi, Mihran Misgari& Dolatkhah, Nida. Effect of probiotic supplementation on blood pressure of females with gestational diabetes mellitus : a randomized double blind controlled clinical trial. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 6, pp.1-10.
https://search.emarefa.net/detail/BIM-767670
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 8-10
Record ID
BIM-767670