Assessment of gender-related differences in vitamin D levels and cardiovascular risk factors in Saudi patients with type 2 diabetes mellitus
Joint Authors
Tabassum, Hajira
Ali, Mir Naiman
Abu Dawud, Manal
Ansar, Sabah
al-Musa, Khalid
Subki, Samiyah
Source
Saudi Journal of Biological Sciences
Issue
Vol. 25, Issue 1 (31 Jan. 2018), pp.31-36, 6 p.
Publisher
Publication Date
2018-01-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Diabetes is a major risk factor for cardiovascular disease (CVD) including stroke, coronary heart disease, and peripheral artery disease.
It remains a leading cause of mortality throughout the world, affecting both women and men.
This investigation was aimed to study gender based differences in cardiovascular risk factors of adult population with type-2 diabetes mellitus (T2DM) and to check the correlation between serum HbA1C, lipid profile and serum vitamin D levels, in T2DM patients of Riyadh, Saudi Arabia.
This hospital-based cross-sectional study involving subjects was divided into two gender based groups; normal male (800), diabetic male (800) and normal female (800) and T2DM females (800).
Bloodsamples were analyzed for fasting glucose (FBG), HbA1c, total cholesterol (TC), triglycerides (Tg), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and serum levels of 25 (OH)-vitamin D in all groups.
All the glycemic control parameters and lipid profile parameters were found to be significantly different in diabetic vs non-diabetic group (p < 0.001) in both genders.
The results also show that vitamin D concentration decreased significantly (p < 0.001) in diabetic patients than the healthy individuals in both the genders.
Vitamin-D and HbA1C were negatively correlated in both males and females in T2DM patients and significant at P < 0.05.
Our study reveals that dyslipidemia remains one of the major risk factors of CVD in T2DM.
In addition to dyslipidemia, decreased levels of vitamin-D associated with increased HbA1C alarms the early diagnosis of Type 2 Diabetes.
American Psychological Association (APA)
Abu Dawud, Manal& Tabassum, Hajira& Ansar, Sabah& al-Musa, Khalid& Subki, Samiyah& Ali, Mir Naiman. 2018. Assessment of gender-related differences in vitamin D levels and cardiovascular risk factors in Saudi patients with type 2 diabetes mellitus. Saudi Journal of Biological Sciences،Vol. 25, no. 1, pp.31-36.
https://search.emarefa.net/detail/BIM-780502
Modern Language Association (MLA)
Abu Dawud, Manal…[et al.]. Assessment of gender-related differences in vitamin D levels and cardiovascular risk factors in Saudi patients with type 2 diabetes mellitus. Saudi Journal of Biological Sciences Vol. 25, no. 1 (Jan. 2018), pp.31-36.
https://search.emarefa.net/detail/BIM-780502
American Medical Association (AMA)
Abu Dawud, Manal& Tabassum, Hajira& Ansar, Sabah& al-Musa, Khalid& Subki, Samiyah& Ali, Mir Naiman. Assessment of gender-related differences in vitamin D levels and cardiovascular risk factors in Saudi patients with type 2 diabetes mellitus. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 1, pp.31-36.
https://search.emarefa.net/detail/BIM-780502
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 35-36
Record ID
BIM-780502