تردد الطفرة C677T في جين MTHFR لدى مرضى داء الزرق في محافظة ذي قار و تأثير داء السكري و التاريخ العائلي عليه

Abstract EN

Glaucoma is a common and non-infection disease that occurs for certain reasons Hypertension in eye is the most important reason for the occurrence of Glaucoma which leads to admage the optic nerve.It affects the both sexes and in most often cases its affects people over the age of forty .

The present study aims to examine the relationship between the mutation C677T and the occurrence of Glaucoma in Thi Qar province .

Asample awas collected and also asample of 100 blood tests was considered as a control grop.

The samples were saved in tubes contains material to prevent coagulation EDTA temperature of (20-) Celsius.DNA was extracted and gene was amplified using Polymerase chain Reaction(PCR) technology and then the gen was cut it using cutter restriction enzyme Hind I.from this study we found that the highest age group infected by the disease was (50-59) with percentage 40% and we also concluded that the hazard ratio increased three time in the patients who have afamily history (OR= 3.73,95%Cl =1.27-1089) while hazard ratio increased by (OR= 2, 95% Cl0.45.10) for the diabetics patients.