Prevalence and clinical investigation of the behcet’s disease in middle east and north Africa : a systematic review and meta-analysis
Joint Authors
Djalalinia, Shirin
Palizgir, Muhammad Tajhi
Mustafaai, Shayan
Mahmudi, Mahdi
Shahram, Farhad
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 19, Issue 4 (30 Apr. 2017), pp.1-7, 7 p.
Publisher
Publication Date
2017-04-30
Country of Publication
United Arab Emirates
No. of Pages
7
Main Subjects
Abstract EN
Context: This systematic review and meta-analysis was performed to determine the prevalence (by overall relative frequency) and clinical information of the Behcet’s disease in Middle East and north Africa (MENA) and it has an important effect on the health policy and performing complementary studies in future.
Evidence Acquisition: We performed this systematic literature review from several databases including PubMed, Scopus and ISI Web of Science according to search strategy with two filters, place (MENA countries) and time (all articles published from Jan 1980 to Jan 2016 were considered).
The keywords such as “Behcet’s syndrome”, “Behcet’s disease”, “triple symptom complex”, “Middle East” were searched.
Out of 4013 relevant articles and according to inclusion and exclusion criteria, 28 papers were selected to study.
To examine the quality of the studies, all papers were evaluated independently by two authors and the Kappa coefficient was 95%.
Afterwards, the critical appraisal was performed by strengthening the reporting of observational studies in epidemiology (STROBE) form.
Due to sever heterogeneity, the pooled prevalence (per 100,000 people) was derived by the random effect model that takes between-study variation into account.
Results: According to the results of the present study, the prevalence rate of BD in Iran was 68; it was after Turkey among MENA.
The pooled prevalence (per 100,000 people) of BD in MENA was 120 (95% CI: 86.8, 166.8) according to the random effect model.
The oral aphthosis was the most frequent symptom among other symptoms and HLA-51 association was its poor prognosis.
Turkey had the highest prevalence (per 100,000 people) of 420 (95%CI: 340, 510) and the lowest prevalence 2.1 related to Kuwait in MENA countries.
Conclusions: There are different statistics about the prevalence rates of the disease that have been published; these different prevalence statistics can be explained by racial and geographical divergence, patient selection and BD diagnosis criteria.
The results of this study can be useful for health policy and other studies which are needed to find the reasons of this prevalence difference.
American Psychological Association (APA)
Palizgir, Muhammad Tajhi& Mahmudi, Mahdi& Qurbani, Mustafa& Djalalinia, Shirin& Mustafaai, Shayan& Shahram, Farhad. 2017. Prevalence and clinical investigation of the behcet’s disease in middle east and north Africa : a systematic review and meta-analysis. Iranian Red Crescent Medical Journal،Vol. 19, no. 4, pp.1-7.
https://search.emarefa.net/detail/BIM-796822
Modern Language Association (MLA)
Qurbani, Mustafa…[et al.]. Prevalence and clinical investigation of the behcet’s disease in middle east and north Africa : a systematic review and meta-analysis. Iranian Red Crescent Medical Journal Vol. 19, no. 4 (Apr. 2017), pp.1-7.
https://search.emarefa.net/detail/BIM-796822
American Medical Association (AMA)
Palizgir, Muhammad Tajhi& Mahmudi, Mahdi& Qurbani, Mustafa& Djalalinia, Shirin& Mustafaai, Shayan& Shahram, Farhad. Prevalence and clinical investigation of the behcet’s disease in middle east and north Africa : a systematic review and meta-analysis. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 4, pp.1-7.
https://search.emarefa.net/detail/BIM-796822
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 6-7
Record ID
BIM-796822