Evaluation of prebiotic (β-glucan)‎ against toxicity of aflatoxin B1 on immune status of cyprinus carpio L

Abstract EN

The aim of this study was to assess the effect of prebiotic (β-glucan) against toxicity of aflatoxin B1 (AFB1) on immune status of Cyprinus carpio L., Six treatments were used, including a control diet (G1) that had different combinations of AFB1 and/or 1% β-glucan.

This include a diet with only β-glucan (G2), 4 mg AFB1 kg dw-1 diet with β-glucan (G3) or without (G5) and six mg AFB1 kg dw-1 diet with β-glucan (G4) or without (G6).

These diets were offered 6 days a week at 3% daily of actual biomass in fiberglass aquaria.

Eight weeks later, the results indicated that, the fish groups (G2, G3, G4) received diet supplemented with prebiotic revealed significant increase (P≤0.05) in non-specific immune response as detected by phagocytic activity, bactericidal activity and respiratory burst activity.

Enzymes (ALT, AST), total proteins, albumin and globulin also showed significant increase in fish groups (G2, G3,G4) received diet supplemented with prebiotic compared to G5 and G6 and to control group (G1).

These results suggested that prebiotic fed fish groups showed a high resistance against toxicity of AFB1