تقييم التكافؤ الحيوي العلاجي للمستحضر السايبرمثرين البيطري من مناشئ مختلفة

Other Title(s)

Evaluation of the therapeutic bioequivalence for veterinary formulation of cypermethrin from different origins

Joint Authors

خيرية أحمد مصطفى
شندالة، محمد خالد

Source

المجلة العراقية للعلوم البيطرية

Publisher

University of Mosul College of Veterinary Medicine

Publication Date

2012-12-31

Country of Publication

Iraq

No. of Pages

7

Main Subjects

Zoology
Veterinary Medicine

Topics

• Drugs
• Insecticides
• Therapeutic use
• Therapeutic equivalency

English Abstract

The bioequivalence are comparison of therapeutic efficacy of veterinary formulations from different origins containing the same active substance thus, the aim of the present study was to compare the efficacy of cypermethrin insecticides for both Jordanian and Indian origins for treatment of sheep were naturally infected with psoroptic mange in dependent on the changes of scores of infection severity, differential leukocyte count and monitor the reinfection (reappearance of skin lesions).

Sheep were naturally infected with psoroptic mange and treated with dip solution cypermethrin twice (14-day interval between them) 1/1000 dilution from both origins demonstrate significantly decreased scores of infected severity at days 7, 14, 21, 28 compared with zero day (before treatment) accompanied with positive changes in the DLC manifested by significant decrease in percentages of both eosinophils and neutrophils with occurrences significant increase in percentage of both lymphocytes and monocytes at days 7, 14, 21, 28 compared with zero day (before treatment).In addition, insecticides provided protection against infection with psoroptic mange because reinfection did not occur after 4 weeks from the second treatment with insecticide.In conclusion, both Jordanian and Indian origins of cypermethrin insecticide were equally in their therapeutic efficacy

Data Type

Conference Papers

Record ID

BIM-830787

• APA
• MLA
• AMA